25605-64-5

Upstream product

• 13343-63-0 benzyl 4,6-O-benzylidene-2-acetylamino-2-deoxy-α-D-glucopyranoside 
• 908094-04-2 phenyldiazomethane 
• 2862-03-5 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside 

Downstream Products

• 25605-65-6 benzyl 2-acetamido-3-O-<(R)-1-(benzyloxycarbonyl)ethyl>-2-deoxy-α-D-glucopyranoside 
• 108431-14-7 benzyl 2-acetamido-3-O-<(R)-1-(benzyloxycarbonyl)ethyl>-2-deoxy-α-D-glucopyranoside 6-(octadecyl phenyl phosphate) 
• 108431-11-4 benzyl 2-acetamido-3-O-<(R)-1-(benzyloxycarbonyl)ethyl>-2-deoxy-α-D-glucopyranoside 6-(diphenyl phosphate) 

Relevant academic research and scientific papers

Preparation of glucosaminyl muramic acid derivatives

The present invention provides a method for the preparation of disaccharides, such as glucosaminyl muramic acids peptides and derivatives. The method includes condensing a protected muramic acid ester with a 1-organothio- or 1-fluoroglucosamine derivative in the presence of a suitable promoter to produce a protected glucosaminyl muramic acid ester. The protected glucosaminyl muramic acid ester may be used to prepare disaccharide peptides, such as N-acetylglucosaminyl-N-acetylmuramyl dipeptides, which have demonstrated immunological activity. Protected muramic acid esters and 1-organothio- or 1-fluoro- glucosamine compounds which may be employed as intermediates in the method are also provided.