2562-77-8

Basic information

• Product Name: 2-(4-BIPHENYLYL)BENZIMIDAZOLE
• Synonyms: 2-(4-BIPHENYLYL)BENZIMIDAZOLE;2-Biphenyl-4-yl-1H-benzoimidazole
• CAS NO: 2562-77-8
• Molecular Formula: C₁₉H₁₄N₂
• Molecular Weight: 270.334
• Mol File: 2562-77-8.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 493.5°Cat760mmHg
• Flash Point: 268.1°C
• Appearance: /
• Density: 1.197g/cm³
• Vapor Pressure: 7.02E-10mmHg at 25°C
• Refractive Index: 1.685
• CAS DataBase Reference: 2-(4-BIPHENYLYL)BENZIMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-BIPHENYLYL)BENZIMIDAZOLE(2562-77-8)
• EPA Substance Registry System: 2-(4-BIPHENYLYL)BENZIMIDAZOLE(2562-77-8)

Safety Data

• Hazardous Substances Data: 2562-77-8(Hazardous Substances Data)

Usage

Structure

Benzimidazole derivative with a biphenyl group attached to the core

Potential applications

Pharmaceutical and material science

Specific use

Fluorescent dye, stabilizer for organic light emitting diodes (OLEDs)

Research interest

Development of new drugs and materials

Unique properties

Structural properties and potential biological activities

InChI:InChI=1/C19H14N2/c1-2-6-14(7-3-1)15-10-12-16(13-11-15)19-20-17-8-4-5-9-18(17)21-19/h1-13H,(H,20,21)

Upstream product

• 2920-38-9 4-cyano-1,1'-biphenyl 
• 95-54-5 1,2-diamino-benzene 
• 2622-74-4 2-(4-bromophenyl)-1H-benzimidazole 
• 143-66-8 sodium tetraphenyl borate 
• 3365-13-7 [1,1':4',1''-terphenyl]-2-carbaldehyde 
• 3597-91-9 biphenyl-4-yl methanol 
• 538-51-2 benzylidene phenylamine 
• 40143-27-9 biphenyl-4-carbaldehyde oxime 
• 42202-94-8 N-hydroxy-[1,1'-biphenyl]-4-carbimidoyl chloride 
• 3218-36-8 4-Phenylbenzaldehyde 
• 4857-06-1 2-chloro-1H-benzoimidazole 
• 5122-94-1 4-biphenylboronic acid 
• 873-75-6 4-bromobenzenemethanol 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1081111-50-3 2-(4-biphenyl)-1-{3-[4-(3-acetylaminophenyl)piperidin-1-yl]propyl}-1H-benzimidazole 
• 1228261-49-1 6-phenyl-benzo[4,5]imidazo[1,2-f]phenanthridine 

Relevant articles and documents

Experimental and theoretical investigation of intramolecular cooperativity in cyclic benzene trimer motif

A series of new symmetrical tripodal molecules 1a-4b with a central benzene scaffold substituted with methyl/ethyl groups and three benzimidazolyl units having a bithiophene/biphenyl/5-alkylthiophene motif at the 2-position via a-CH2-unit were

Direct synthesis of 2-substituted benzimidazoles: Via dehydrogenative coupling of aromatic-diamine and primary alcohol catalyzed by a Co complex

A Co(ii) complex with a stable structure was designed and synthesized with quinalic acid and Co (OAc)2·4H2O. The single crystal structure of the complex was characterized by X-ray diffraction. A dehydrogenative coupling of aromatic diamines and primary alcohols was developed by using the Co(ii) complex as the catalyst to synthesize 2-substituted benzimidazole. A series of 2-substituted benzimidazoles were obtained with good to excellent yields under mild reaction conditions. In addition, a compound with inhibitory Parkinson's activity was synthesized on a gram-scale by using this method. Finally, the reaction mechanism was proposed and the energy changes in the reaction process were simulated by density functional theory (DFT).

Transforming Oxadiazolines through Nitrene Intermediates by Energy Transfer Catalysis: Access to Sulfoximines and Benzimidazoles

Subtle differences in reaction conditions facilitated unprecedented photocatalytic reactions of oxadiazolines by energy transfer catalysis. A set of compounds, sulfoximines and benzimidazoles, were ingeniously prepared from oxadiazolines via nitrene intermediates by photocatalytic N-O/C-N bond cleavages. The synthesis of sulfoximines was realized through intermolecular N-S bond formation between nitrene intermediates and sulfoxides, whereas benzimidazoles were obtained via intramolecular aromatic substitution of the nitrene to the tethered aryl substituent.