256341-88-5

Basic information

• Product Name: (3aS,4R,6R,7R,7aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-4-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol
• Synonyms: (3aS,4R,6R,7R,7aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-4-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol
• CAS NO: 256341-88-5
• Molecular Weight: 426.649
• Mol File: 256341-88-5.mol

Chemical Properties

• CAS DataBase Reference: (3aS,4R,6R,7R,7aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-4-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3aS,4R,6R,7R,7aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-4-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol(256341-88-5)
• EPA Substance Registry System: (3aS,4R,6R,7R,7aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-4-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol(256341-88-5)

Safety Data

• Hazardous Substances Data: 256341-88-5(Hazardous Substances Data)

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 126092-08-8 phenyl 2,3-di-O-isopropylidene-1-thio-α-D-mannopyranoside 

Downstream Products

• 306726-33-0 C₅₅H₇₆O₁₄SeSi 
• 306726-37-4 C₅₆H₇₄O₁₆Si 
• 306726-36-3 C₄₉H₆₈O₁₇SSi 
• 306726-35-2 C₄₉H₇₀O₁₅Si 
• 306726-47-6 C₄₇H₆₂O₁₆Si 
• 306726-44-3 C₄₇H₅₄O₁₆ 
• 306726-34-1 C₄₉H₆₈O₁₃Si 
• 306726-46-5 C₄₁H₄₈O₁₆ 
• 306726-45-4 C₄₀H₅₀O₁₅ 
• 306726-32-9 benzoic acid 3-benzyloxy-2-(4-benzyloxy-3-methoxy-6-methoxymethyl-5-triisopropylsilanyloxy-tetrahydro-pyran-2-yloxy)-5-[4-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-3-phenylselanyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester 
• 256342-07-1 C₆₃H₉₁ClO₁₅SeSi₂ 
• 1053712-31-4 C₆₁H₉₀O₁₅SeSi₂ 
• 256342-28-6 C₆₁H₇₄O₁₇Si 
• 256342-08-2 3-benzyloxy-2-(4-benzyloxy-3-methoxy-6-methoxymethyl-5-triisopropylsilanyloxy-tetrahydro-pyran-2-yloxy)-5-[4-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-3-phenylselanyl-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-ol 

Relevant articles and documents

Total synthesis of everninomicin 13,384-1 - Part 2: Synthesis of the FGHA2 fragment

The stereoselective synthesis of everninomicin's 13,384-1 (1) FGHA2 fragment (2) in a suitable form for incorporation into the final target (1) is described. The construction of the FG 1,1′-disaccharide linkage relied on a new method based on tin-acetal chemistry, while for the GH orthoester bridge, a number of approaches were explored. Final success for the latter construction came when a novel 1,2-phenylseleno migration reaction was applied to couple rings G and H, followed by ketene acetal and orthoester formation.