256382-74-8

Upstream product

• 90319-52-1 (4R)-phenyl-2-oxazolidinone 
• 106-96-7 propargyl bromide 

Downstream Products

• 256382-50-0 (4R)-4-phenyl-3-(1,2-propadienyl)-2-oxazolidinone 
• 653602-11-0 4-phenyl-3-(3-trimethylsilanyl-prop-2-ynyl)oxazolidin-2-one 

Relevant academic research and scientific papers

NECROSIS INHIBITORS

The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.

First stereoselective inverse demand [4 + 2] cycloaddition reactions of novel chiral allenamides with heterodienes. Preparation of highly functionalized 2-arylpyranyl heterocycles

matrix presented The first stereoselective inverse demand [4 + 2] cycloaddition reactions of chiral allenamides with heterodienes are described here. These reactions lead to stereoselective synthesis of highly functionalized pyranyl heterocycles. A mechan