256386-08-0

Usage

Chemical structure

A benzene ring with two bromine atoms at positions 1 and 3, and a dibromomethyl group attached at position 5.

Reactivity

Highly reactive compound.

Applications

Primarily used as a chemical intermediate in the production of various organic compounds.

Industries

Commonly used in the synthesis of pharmaceuticals, agrochemicals, and polymers.

Research and development

Used as a building block in the development of new materials and research applications.

Environmental and health concerns

Considered a potential environmental and human health hazard due to its toxic and potentially carcinogenic properties.

Safety precautions

Appropriate handling, storage, and disposal measures should be taken to minimize exposure and environmental impact.

Upstream product

• 1611-92-3 3,5-dibromotoluene 
• 626-39-1 1,3,5-trisbromobenzene 
• 56990-02-4 3,5-dibromobenzaldehyde 

Downstream Products

• 256386-21-7 C₈₈H₆₄Br₈O₈ 
• 935537-58-9 C₁₀₀H₁₂₀Br₈O₈ 

Relevant academic research and scientific papers

Synthesis of Water-Soluble Deep-Cavity Cavitands

An efficient, four-step synthesis of a range of water-soluble, deep-cavity cavitands is presented. Key to this approach are octahalide derivatives (4, X = Cl or Br) that allow a range of water-solubilizing groups to be added to the outer surface of the co

A novel C2-symmetric bisphosphane ligand with a chiral cyclopropane backbone: Synthesis and application in the Rh(I)-catalyzed asymmetric 1,4-addition of arylboronic acids

The synthesis of a novel C2-symmetric bisphosphane ligand was accomplished starting from trans-(2R,3R)-bis(3′,5′-diphenylphenyl) cyclopropane-1,1-dimethanol as a key intermediate. This ligand was tested in the asymmetric rhodium(I)-catalyzed 1,

Guest binding and orientation within open nanoscale hosts

The synthesis of three different nanoscale molecular hosts is reported. These cavitands each possess a highly preorganized cavity with an open portal (nearly 1 nm wide), by which guests can enter and egress the cavity. Additionally, these hosts are deep-functionalized with a crown of weakly acidic benzal C-H groups which can form a variety of noncovalent interactions with guest molecules residing within the cavity. Thirty-one guests were examined for their propensity to form complexes with the hosts. Guests that possess halogen atoms were the strongest binders, suggesting the formation of polydentate C-H···X-R hydrogen bonds with the deep crown of benzal hydrogens. Exchange rates between the free and bound states were noted to be dependent on the size of the guest and the solvent used to study complexation. In general, stronger binding and slower exchange were noted for complexations carried out in DMSO with highly complementary guests. The orientation of each guest within the cavity was determined using either EXSY NMR spectroscopy or 1H NMR shift data, Cumulatively these results showed that the principal factors directing orientation were interactions with the benzal groups and the type of solvent. Van't Hoff analyses of selected complexations were also carried out. As well as revealing that all complexations were entropically unfavorable, these experiments provided support for guest orientation determinations, and gave an estimation that the formation of a C-H···I-R hydrogen bond releases between 1 and 1.5 kcalmol-1.

Synthesis, characterization, and optical response of dipolar and non-dipolar poly(phenylenevinylene) dendrimers

New dipolar and non-dipolar poly(phenylenevinylene) dendrimers bearing electron-donating and electron-withdrawing groups have been efficiently synthesized using Heck and Horner-Wadsworth-Emmons reactions. The photoluminescence of these systems may be tuned in the blue zone by choosing the appropriate peripheral groups. Despite the meta-substitution pattern, large Stokes shifts can be observed when π-donor and π-acceptor groups are connected by a m-phenylenevinylene system.