256389-53-4

Basic information

• Product Name: (R)-2-(methoxycarbonyl)-2-(3-methoxyphenyl)pent-4-enoic acid
• Synonyms: (R)-2-(methoxycarbonyl)-2-(3-methoxyphenyl)pent-4-enoic acid
• CAS NO: 256389-53-4
• Molecular Weight: 264.278
• Mol File: 256389-53-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-(methoxycarbonyl)-2-(3-methoxyphenyl)pent-4-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-(methoxycarbonyl)-2-(3-methoxyphenyl)pent-4-enoic acid(256389-53-4)
• EPA Substance Registry System: (R)-2-(methoxycarbonyl)-2-(3-methoxyphenyl)pent-4-enoic acid(256389-53-4)

Safety Data

• Hazardous Substances Data: 256389-53-4(Hazardous Substances Data)

Upstream product

• 3897-04-9 methyl 2-acetylpent-4-enoate 
• 256389-58-9 (R)-methyl 2-formyl-2-(3-methoxyphenyl)pent-4-enoate 

Downstream Products

• 791049-50-8 (S)-2-(2-Benzylamino-ethyl)-2-(3-methoxy-phenyl)-pent-4-enoic acid methyl ester 
• 256389-68-1 (S)-3-Allyl-1-benzyl-5-methoxy-3-(3-methoxy-phenyl)-pyrrolidin-2-one 
• 256389-61-4 (S)-2-(3-Methoxy-phenyl)-2-((E)-2-methoxy-vinyl)-pent-4-enoic acid methyl ester 
• 256389-64-7 (S)-2-(3-Methoxy-phenyl)-2-(2-oxo-ethyl)-pent-4-enoic acid methyl ester 
• 256389-55-6 (R)-2-Hydroxymethyl-2-(3-methoxy-phenyl)-pent-4-enoic acid methyl ester 
• 256389-58-9 (R)-methyl 2-formyl-2-(3-methoxyphenyl)pent-4-enoate 

Relevant articles and documents

Catalytic asymmetric insertion of diazoesters into Aryl-CHO bonds: Highly enantioselective construction of chiral all-carbon quaternary centers

This paper describes a catalytic enantioselective route to synthesize functionalized all-carbon quaternary acyclic systems via a boron Lewis acid-promoted formal C-C insertion of diazoesters into aryl-CHO bonds. In the presence of chiral (S)-oxazaborolidinium cation 1d as a catalyst, the reaction proceeded in good yield (up to 83%) with good regioselectivity (up to 88:12) and excellent enantioselectivity (up to 99% ee). The synthetic potential of this method was illustrated by conversion of the products to both α-and β-amino esters.