256397-92-9

Upstream product

• 193812-02-1 (R)-(but-3-yn-2-yloxy)(tert-butyl)dimethylsilane 
• 256397-91-8 [2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]aldehyde 
• 75858-32-1 [2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]methanol 

Downstream Products

• 608530-16-1 (1R,4R)-1-[2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]-4-O-tert-butyldimethylsilyl-1-O-(4-nitrobenzoyl)pent-2-yne-1,4-diol 
• 608530-02-5 (1R,4R)-1-[2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]-4-O-(ethoxycarbonyl)pent-2-ene-1,4-diol 
• 608530-18-3 (1R,4R)-1-[2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]-4-O-(ethoxycarbonyl)pent-2-yne-1,4-diol 
• 608530-03-6 methyl (3S,4E,6R)-6-[2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]-6-hydroxy-2-(methoxycarbonyl)-3-methylhex-4-enoate 
• 608530-17-2 (1R,4R)-1-[2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]-1-O-(4-nitrobenzoyl)pent-2-yne-1,4-diol 
• 608530-01-4 (1R,4R)-1-[2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]-4-O-(ethoxycarbonyl)-1-O-(4-nitrobenzoyl)pent-2-yne-1,4-diol 
• 608530-19-4 methyl (3S,4E,6R)-6-[2,3-di-O-benzyl-4,6-dideoxy-6-(methoxycarbonyl)-D-gluco-β-C-pyranosyl]-6-(2,4-dichlorobenzoyloxy)-2-(methoxycarbonyl)-3-methylhex-4-enoate 

Relevant academic research and scientific papers

New aspects in the stereoselective ethynylation of β-C-glycoside aldehydes. Application to the synthesis of an ambruticin fragment

Stereoselective ethynylation of functionalized β-C-glycosyl aldehydes has been achieved with various organometallic alkynes, The diastereoselectivity is highly dependent on the organometallic alkyne and on the functionalization on the C-6 position of the

A new synthetic approach toward (+)-ambruticin analogs: Preparation of a C10-C11 cis-isomer fragment

A new methodology has been applied to synthesize an isomer of the west part of (+)-ambruticin based on an efficient asymmetric de novo access to the A unit and sequential stereospecific reactions catalyzed by Pd0 for the construction of the B unit.