256411-75-3Relevant academic research and scientific papers
Synthesis and in vitro cytotoxicity of hexacyclic Camptothecin analogues
Jew, Sang-Sup,Kim, Hee-Jin,Goo Kim, Myoung,Roh, Eun-Young,Il Hong, Chung,Kim, Joon-Kyum,Lee, Jun-Hee,Lee, Heesoon,Park, Hyeung-Geun
, p. 3203 - 3206 (2007/10/03)
A series of C(7)-N-alkylaminoethyl-C(10), C(11)-methylenedioxy- and ethylenedioxy-camptothecin (3a-g, 4a-h) were prepared. Their syntheses and in vitro cytotoxicity were reported. Among 15 derivatives, 3a and 3b showed more potent cytotoxicity than Campto
