256418-57-2Relevant academic research and scientific papers
Effect of Ligand Modification on Rhodium-Catalyzed Homogeneous Hydroformylation in Supercritical Carbon Dioxide
Palo, Daniel R.,Erkey, Can
, p. 81 - 86 (2008/10/08)
Several fluoroalkyl- and fluoroalkoxy-substituted tertiary arylphosphines were synthesized and investigated in the homogeneous catalytic hydroformylation of 1-octene using HRh-(CO)L3 (L = tertiary arylphosphine). The activity of the rhodium complex (formed in situ from Rh(CO)2(acac) and L) increased with decreasing basicity of the phosphine according to the series [3,5-(CF3)2C6H3]3P > [4-CF3C6H4]3P ≈ [3-CF3C6H4]3P > [4-CF3C6H4]3P > [4-F(CF2)4(CH2)3C6H 4]3P. The very weakly basic phosphine (C6F5)3P did not complex with Rh(CO)2(acac), most likely due to a combination of electronic and steric factors. Steric effects did not play a role in either the activity or selectivity of the rhodium catalysts that were formed under hydroformylation conditions.
