256475-04-4

Upstream product

• 402-43-7 p-trifluoromethylphenyl bromide 
• 1571-08-0 methyl 4-formylbenzoate 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 619-44-3 methyl 4-iodobenzoate 
• 1126-46-1 Methyl 4-chlorobenzoate 

Downstream Products

• 1252782-17-4 methyl 4-(fluoro(4-(trifluoromethyl)phenyl)methyl)benzoate 
• 613240-14-5 4-(4-trifluoromethyl-benzyl)-benzoic Acid Methyl Ester 

Relevant academic research and scientific papers

Nickel- and chromium-catalysed electrochemical coupling of aryl halides with arenecarboxaldehydes

Electrochemical arylation of arenecarboxaldehydes using a stainless steel sacrificial anode in the presence of Ni catalysts afforded the corresponding arylated secondary alcohols in good yields.

AMINO-PYRROLIDINE-AZETIDINE DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds, and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof, are represented by Formula

Compounds that modulate PPAR activity and methods for their preparation

This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing disipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of supressing appetite and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.