256475-59-9 Usage
Type of compound
Diazepane derivative
Type of compound
It is a diazepane derivative, which means it is derived from diazepane, a heterocyclic compound with a seven-membered ring containing two nitrogen atoms.
Ring structure
Seven-membered diazepane ring
Ring structure
The compound contains a seven-membered diazepane ring, which is the core structure of this molecule.
Substitution pattern
1,4
Substitution pattern
The 1,4 substitution pattern refers to the positions of the substituents on the diazepane ring. In this case, the substituents are attached to the 1st and 4th positions of the ring.
Presence of a 4-methoxy-phenyl group
Yes
Presence of a 4-methoxy-phenyl group
The molecule contains a 4-methoxy-phenyl group, which is a phenyl group (a six-carbon aromatic ring) with a methoxy group (-OCH3) attached to the 4th carbon.
Classification
Phenethylamine class of compounds
Classification
Due to the presence of the 4-methoxy-phenyl group, 1-[2-(4-methoxy-phenyl)-ethyl]-[1,4]diazepane is classified as a member of the phenethylamine class of compounds. Phenethylamines are a group of compounds that have a phenyl ring attached to an ethylamine group.
Pharmacological properties
Potential applications in medicinal chemistry and drug development
Pharmacological properties
As a diazepane derivative and a member of the phenethylamine class, 1-[2-(4-methoxy-phenyl)-ethyl]-[1,4]diazepane may have various pharmacological properties and potential applications in the field of medicinal chemistry and drug development. These properties could include effects on the central nervous system, such as sedation, anxiolysis, or muscle relaxation.
Check Digit Verification of cas no
The CAS Registry Mumber 256475-59-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,6,4,7 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 256475-59:
(8*2)+(7*5)+(6*6)+(5*4)+(4*7)+(3*5)+(2*5)+(1*9)=169
169 % 10 = 9
So 256475-59-9 is a valid CAS Registry Number.
256475-59-9Relevant academic research and scientific papers
Non-imidazole histamine H3 ligands. Part I. Synthesis of 2-(1-piperazinyl)- and 2-(hexahydro-1H-1,4-diazepin-1-yl)benzothiazole derivatives as H3-antagonists with H1 blocking activities
Walczynski, Krzysztof,Guryn, Roman,Zuiderveld, Obbe P.,Timmerman, Henk
, p. 684 - 694 (2007/10/03)
New 2-(1-Piperazinyl)- and 2-(hexahydro-1H-1,4-diazepin-1-yl)benzothiazoles were prepared and tested as H1- and H3-receptor antagonists. A number of compounds showed weak H1-antagonistic activity, with pA2 values ranging from 5.5 to 6.1. The simple alkyl substituted, 2-[1-(4-methyl and 4-ethyl)piperazinyl] analogues show increasing, moderate H3-antagonistic activity (pA2=6.0, and pA2=7.0). The compounds with 4-phenylalkyl substitution, for both the piperazinyl and the hexahydro-1H-1,4-diazepin-1-yl homologues series, regardless of the different physicochemical properties of the para substituents at the phenyl ring, showed weak H3-antagonistic activity with pA2 values ranging from 4.4 to 5.6. Copyright (C) 1999 Elsevier Science S.A.
