256494-91-4

Upstream product

• 218967-53-4 2'-O-(tert-butyldimethylsilyl)-3'-deoxy-3-(hydroxylamino)uridine 
• 90813-54-0 2',5'-bis-O-tert-butyldimethylsilyl-3'-ketouridine 
• 54925-66-5 2',5'-bis-O-(tert-butyldimethylsilyl)uridine 
• 256494-88-9 2'-O-(tert-butyldimethylsilyl)-3'-(trifluoroacetamido)-3'-deoxyuridine 

Downstream Products

• 256494-87-8 2'-O-(tert-butyldimethylsilyl)-3'-[(N-(9-fluorenylmethyloxycarbonyl)thiocarbomoyl)amino]-5'-O-(4-monomethoxytrityl)-3'-deoxyuridine 

Relevant academic research and scientific papers

Replacement of the phosphorodiester linkages of RNA with guanidinium linkages: the solid-phase synthesis of ribonucleic guanidine.

[reaction: see text] Replacement of the negatively charged phosphodiester linkages of RNA with positively charged guanidinium linkages provides the polycationic ribonucleic guanidine (RNG). RNG is anticipated to bind strongly to target DNA/RNA through the

Synthesis of ribonucleic guanidine: Replacement of the negative phosphodiester linkages of RNA with positive guanidinium linkages

Replacement of the negatively charged phosphodiester linkages of RNA with positively charged guanidinium linkages provides the polycationic ribonucleic guanidine (RNG). RNG is designed to bind strongly to target DNA/RNA through the specific interactions o