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1H-Benzimidazole,1-(2-pyridinyl)-(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

25660-37-1

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25660-37-1 Usage

Type of compound

Heterocyclic

Structure

Benzene ring fused to an imidazole ring and a pyridine ring

Usage in pharmaceutical industry

Building block for synthesis of biologically active molecules

Potential therapeutic applications

Treatment of various diseases and disorders

Other potential applications

Material science, coordination chemistry as a ligand

Importance

Versatile and valuable building block in organic synthesis and drug discovery

Check Digit Verification of cas no

The CAS Registry Mumber 25660-37-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,6,6 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 25660-37:
(7*2)+(6*5)+(5*6)+(4*6)+(3*0)+(2*3)+(1*7)=111
111 % 10 = 1
So 25660-37-1 is a valid CAS Registry Number.

25660-37-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-pyridin-2-ylbenzimidazole

1.2 Other means of identification

Product number -
Other names 1-pyridin-2-yl-1H-benzoimidazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:25660-37-1 SDS

25660-37-1Relevant academic research and scientific papers

Visible-light photoredox catalysis: Selective reduction of carbon dioxide to carbon monoxide by a nickel N-heterocyclic carbene-isoquinoline complex

Thoi, V. Sara,Kornienko, Nikolay,Margarit, Charles G.,Yang, Peidong,Chang, Christopher J.

, p. 14413 - 14424 (2013)

The solar-driven reduction of carbon dioxide to value-added chemical fuels is a longstanding challenge in the fields of catalysis, energy science, and green chemistry. In order to develop effective CO2 fixation, several key considerations must be balanced, including (1) catalyst selectivity for promoting CO2 reduction over competing hydrogen generation from proton reduction, (2) visible-light harvesting that matches the solar spectrum, and (3) the use of cheap and earth-abundant catalytic components. In this report, we present the synthesis and characterization of a new family of earth-abundant nickel complexes supported by N-heterocyclic carbene-amine ligands that exhibit high selectivity and activity for the electrocatalytic and photocatalytic conversion of CO2 to CO. Systematic changes in the carbene and amine donors of the ligand have been surveyed, and [Ni( Prbimiq1)]2+ (1c, where Prbimiq1 = bis(3-(imidazolyl)isoquinolinyl)propane) emerges as a catalyst for electrochemical reduction of CO2 with the lowest cathodic onset potential (Ecat = -1.2 V vs SCE). Using this earth-abundant catalyst with Ir(ppy)3 (where ppy = 2-phenylpyridine) and an electron donor, we have developed a visible-light photoredox system for the catalytic conversion of CO2 to CO that proceeds with high selectivity and activity and achieves turnover numbers and turnover frequencies reaching 98,000 and 3.9 s-1, respectively. Further studies reveal that the overall efficiency of this solar-to-fuel cycle may be limited by the formation of the active Ni catalyst and/or the chemical reduction of CO2 to CO at the reduced nickel center and provide a starting point for improved photoredox systems for sustainable carbon-neutral energy conversion.

NHC-containing manganese(I) electrocatalysts for the two-electron reduction of CO2

Agarwal, Jay,Shaw, Travis W.,Stanton, Charles J.,Majetich, George F.,Bocarsly, Andrew B.,Schaefer, Henry F.

, p. 5152 - 5155 (2014)

The synthesis and characterization of the first catalytic manganese N-heterocyclic carbene complexes are reported: MnBr(N-methyl-N'-2- pyridylbenzimidazol-2-ylidine)(CO)3 and MnBr(N-methyl-N'-2- pyridylimidazol-2-ylidine)(CO)3. Both new species mediate the reduction of CO2 to CO following two-electron reduction of the MnI center, as observed with preparative scale electrolysis and verified with 13CO2. The two-electron reduction of these species occurs at a single potential, rather than in two sequential steps separated by hundreds of millivolts, as is the case for previously reported MnBr(2,2'-bipyridine)(CO)3. Catalytic current enhancement is observed at voltages similar to MnBr(2,2'-bipyridine)(CO)3. Catalytic manganese N-heterocyclic carbene complexes have been synthesized and characterized: [MnBrL(CO)3] (see scheme; L=N-methyl-N'-2- pyridylbenzimidazol-2-ylidine or N-methyl-N'-2-pyridylimidazol-2-ylidine). Both species mediate the reduction of CO2 to CO following two-electron reduction of the MnI center at a single potential, as observed with preparative scale electrolysis and verified with 13CO2.

Four-coordinate N-heterocyclic carbene (NHC) copper(I) complexes with brightly luminescence properties

Liu, Shaobo,Xu, Shengxian,Wang, Jinglan,Zhao, Feng,Xia, Hongying,Wang, Yibo

, p. 584 - 599 (2017)

Three four-coordinate N-heterocyclic carbene (NHC) copper(I) complexes, [Cu(Py-Im)(POP)](PF6) (P1), [Cu(Py-BenIm)(POP)](PF6) (P2), and [Cu(Py-c-BenIm)(POP)](PF6) (P3) (Py-Im?=?3-methyl-1-(pyridin-2-yl)-1H-imidazolylidene,

Re(I) NHC Complexes for Electrocatalytic Conversion of CO2

Stanton, Charles J.,Machan, Charles W.,Vandezande, Jonathon E.,Jin, Tong,Majetich, George F.,Schaefer, Henry F.,Kubiak, Clifford P.,Li, Gonghu,Agarwal, Jay

, p. 3136 - 3144 (2016)

The modular construction of ligands around an N-heterocyclic carbene building block represents a flexible synthetic strategy for tuning the electronic properties of metal complexes. Herein, methylbenzimidazolium-pyridine and methylbenzimidazolium-pyrimidi

Photophysical processes of some benzimidazole derivatives

Chen, Zhaobin,Zhang, Caihong,Feng, Liheng

, p. 592 - 595 (2005)

The photophysical properties of N-(α-naphthyl)-benzimidazole (α-NABI), N-(β-naphthyl)-benzimidazole (β-NABI) and N-(α-pyridyl)-benzimidazole (α-PYBI) were studied and α-NYBI exhibit intramolecular charge transfer fluorescence in polar solvents. The fluorescence of benzimidazoles can be quenched by acetic acid and the existence of exciplexes was observed between the benzimidazole derivatives and acetic acid. Particularly, the maximum emission peak of solution of α-PYBI in mixed solvent, ether and acetic acid, presents obvious red-shift with the increase of concentration of acetic acid in the mixed solvent.

Monodentate Benzo[d]imidazole-Based Iridium(III) Complexes and Their Dual Fluorescent and Phosphorescent Emissions

Ryu, Chan Hee,Kim, Mingi,Sohn, Changho,Hong, Ju Hyun,Im, Sehee,Kim, So Yeon,Lee, Kang Mun

, p. 176 - 183 (2020)

We herein reported the preparation of three heteroleptic iridium complexes possessing the monodentate benzo[d]imidazole ligand, namely IrBzH (bis[2-(4,6-difluorophenyl)pyridinato-C^N](1-pyridin-2-yl)-1H-benzo[d]imidazolate)iridium(III)), IrBzCN (bis[2-(4,6-difluorophenyl)pyridinato-C^N](2-(1H-benzo[d]imidazolate-1-yl)isonicotinonitrile)iridium(III)), and IrBzBr (bis[2-(4,6-difluorophenyl)pyridinato-C′N](1-(4-bromopyridin-2-yl)-1H-benzo[d]imidazolate)iridium(III)). The successful preparation of these complexes was confirmed by multinuclear NMR spectroscopy and elemental analysis, while the molecular structures were determined by X-ray diffraction. The photoluminescence spectra of all three complexes in toluene at ambient temperature exhibited a dual-emissive pattern in the high- and low-energy regions. For IrBzCN and IrBzBr, the emissions were simultaneous in accordance with the excitation energies (λem = 342 and 370 nm), indicating that exhibiting both fluorescent (in the high-energy region) and phosphorescent (in the low-energy region) emissions is an inherent property of these complexes. Time-dependent density functional theory calculations verified that each fluorescent emission of the Ir complexes is associated with a ligand-to-ligand charge transfer transition, and the phosphorescent emission can be attributed to typical triplet metal-to-ligand charge transfer transitions between Ir3+ and the difluorophenylpyridine ligand.

Ligand-free copper-catalysed coupling reaction of heteroaryl bromides with imidazole and benzimidazole

Wu, Xiang-Mei,Wang, Yan

, p. 555 - 557 (2009)

The synthesis of N-heteroarylimidazoles by coupling heteroaryl bromides with imidazole or benzimidazole under relatively mild conditions using the stable and readily available copper(II) acetate as catalyst and cesium carbonate as base is reported to give products in moderate to good yields.

Functionalization of superparamagnetic Fe3O4@SiO2 nanoparticles with a Cu(II) binuclear Schiff base complex as an efficient and reusable nanomagnetic catalyst for N-arylation of α-amino acids and nitrogen-containing heterocycles with aryl halides

Sardarian,Kazemnejadi,Esmaeilpour

, (2020/10/20)

Fe3O4@SiO2 nanoparticles was functionalized with a binuclear Schiff base Cu(II)-complex (Fe3O4@SiO2/Schiff base-Cu(II) NPs) and used as an effective magnetic hetereogeneous nanocatalyst for the N-arylation of α-amino acids and nitrogen-containig heterocycles. The catalyst, Fe3O4@SiO2/Schiff base-Cu(II) NPs, was characterized by Fourier transform infrared (FTIR) and ultraviolet-visible (UV-vis) analyses step by step. Size, morphology, and size distribution of the nanocatalyst were studied by transmission electron microscopy (TEM), scanning electron microscopy (SEM), and dynamic light scatterings (DLS) analyses, respectively. The structure of Fe3O4 nanoparticles was checked by X-ray diffraction (XRD) technique. Furthermore, the magnetic properties of the nanocatalyst were investigated by vibrating sample magnetometer (VSM) analysis. Loading content as well as leaching amounts of copper supported by the catalyst was measured by inductive coupled plasma (ICP) analysis. Also, thermal studies of the nanocatalyst was studied by thermal gravimetric analysis (TGA) instrument. X-ray photoelectron spectroscopy (XPS) analysis of the catalyst revealed that the copper sites are in +2 oxidation state. The Fe3O4@SiO2/Schiff base-Cu(II) complex was found to be an effective catalyst for C–N cross-coupling reactions, which high to excellent yields were achieved for α-amino acids as well as N-hetereocyclic compounds. Easy recoverability of the catalyst by an external magnet, reusability up to eight runs without significant loss of activity, and its well stability during the reaction are among the other highlights of this catalyst.

Cr-Catalyzed Direct ortho-Aminomethylation of Phenols

Shi, Junbin,Wang, Yubin,Bu, Qingqing,Liu, Binyuan,Dai, Bin,Liu, Ning

, p. 17567 - 17580 (2021/12/17)

We developed a Cr-catalyzed strategy for the regioselective formation of Csp2–Csp3 bonds through the direct and efficient ortho-aminomethylation of N,N-dimethylanilines with phenols. The approach showed excellent site selectivity at the ortho-position of phenols and accommodated broad substrate scope and functional group compatibility for both N,N-dimethylanilines and phenols. Mechanistic studies revealed that the direct ortho-aminomethylation between N,N-dimethylanilines and phenols occurred via an ionic mechanism.

N -Arylation of (hetero)arylamines using aryl sulfamates and carbamates via C-O bond activation enabled by a reusable and durable nickel(0) catalyst

Dindarloo Inaloo, Iman,Majnooni, Sahar,Eslahi, Hassan,Esmaeilpour, Mohsen

, p. 13266 - 13278 (2020/10/07)

An effective and general aryl amination protocol has been developed using a magnetically recoverable Ni(0) based nanocatalyst. This new stable catalyst was prepared on Fe3O4@SiO2 modified by EDTA and investigated by FT-IR, EDX, TEM, XRD, DLS, FE-SEM, XPS, NMR, TGA, VSM, ICP and elemental analysis techniques. The reaction proceeded via carbon-oxygen bond cleavage of (hetero)aryl carbamates and sulfamates under simple and mild conditions without the use of any external ligands. This method demonstrated functional group tolerance in the N-arylation of various nitrogen-containing compounds as well as aliphatic amines, anilines, pyrroles, pyrazoles, imidazoles, indoles, and indazoles with good to excellent yields. Furthermore, the catalyst could be easily recovered by using an external magnetic field and directly reused at least six times without notable reduction in its activity. This journal is

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