256651-55-5Relevant articles and documents
Preparation process 2-6 - dibromobenzoyl chloride
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, (2021/01/24)
The invention discloses a preparation process for 2,6-dibromobenzene methylsulfonyl chloride. The preparation process comprises the following steps: with m-dibromobenzene as a starting raw material, subjecting the m-dibromobenzene to a five-step reaction of acylation, reduction, chlorine substitution, substitution and sulfonyl chlorination so as to obtain a target compound namely the 2,6-dibromobenzene methylsulfonyl chloride. The process provided by the invention uses cheap and easily-available raw materials, has good safety by using NCS to replace chlorine gas as a chlorinating agent, and facilitates practical application.
INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2
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Page/Page column 29, (2008/06/13)
This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A2 enzymes (cPLA2), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLAα). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein.