2569-99-5

Upstream product

• 886-38-4 diphenylcyclopropenone 
• 121104-69-6 C₂₀H₂₁N₃O₄ 
• 111888-57-4 4-methyl-6-methylcarbamoyloxy-1,2-diphenyl-4,6-diazaspiro<2.3>hex-1-en-5-one 

Downstream Products

• 78956-41-9 β-Cyclohexylamino-α,β-diphenylacrylnitril 
• 78956-42-0 β-Benzylamino-α,β-diphenylacrylnitril 
• 78956-43-1 (E)-α,β-Diphenylacrylsaeure-N-benzylamidoxim 
• 78956-45-3 β-Morpholino-α,β-diphenylacrylnitril 
• 78956-44-2 3-Morpholino-4,5-diphenylisoxazol 

Relevant academic research and scientific papers

Cyclopropenone Oximes: Preparation and Reaction with Isocyanates

2,3-Diphenyl-, 2-methyl-3-phenyl-, and 2-methyl-3-(4-methylphenyl)cyclopropenone oxime hydrochlorides (3) were prepared in good yields from the corresponding cyclopropenones and hydroxylamine hydrochloride in methanol.The salts 3 reacted with alkyl and aryl isocyanates in the presence of triethylamine to afford 1 : 2 addition products 4,6-diazaspirohexenones in moderate yields.In contrast, acetone, acetophenone, and cyclohexanone oximes reacted with twice excess of methyl isocyanates to give linear 1 : 1 addition products and benzophenone oxime yielded only 1 : 1 addition product.

Synthesis of Novel 4,6-Diazaspirohex-1-en-5-ones by the Reaction of Diphenylcyclopropenone Oxime with Isocyanates

Diphenylcyclopropenone oxime hydrochloride (3) was prepared in an 83 percent yield from diphenylcyclopropenone and hydroxylamine hydrochloride in methanol.The salt 3 reacted with alkyl and aryl isocyanates in the presence of triethylamine to yield 1:2 add