256955-85-8Relevant articles and documents
3Alpha-hydroxy-3beta-methoxymethyl-substituted steroids and the use thereof
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Page/Page column 5-6, (2010/02/05)
This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein: R1 is H or methyl; R2 is 5α- or 5β-H; R3 is an optionally substituted N-attached heteroaryl group or a group —X—R4; R4 is an optionally substituted carbon-attached heteroaryl group; and X is O, S or N. The invention also is directed to the use of 3α-hydroxy-3β-methoxymethyl-substituted steroids as sedative/hypnotics and for inducing anesthesia.