25698-18-4

Basic information

• Product Name: (R)-2-amino-2-(3,5-dichloro-4-hydroxyphenyl)acetic acid
• Synonyms: (R)-2-amino-2-(3,5-dichloro-4-hydroxyphenyl)acetic acid
• CAS NO: 25698-18-4
• Molecular Weight: 236.054
• Mol File: 25698-18-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-2-amino-2-(3,5-dichloro-4-hydroxyphenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-amino-2-(3,5-dichloro-4-hydroxyphenyl)acetic acid(25698-18-4)
• EPA Substance Registry System: (R)-2-amino-2-(3,5-dichloro-4-hydroxyphenyl)acetic acid(25698-18-4)

Safety Data

• Hazardous Substances Data: 25698-18-4(Hazardous Substances Data)

Upstream product

• 22818-40-2 D-4-hydroxyphenylglycine 
• 69598-75-0 complestatin 

Downstream Products

• 26973-43-3 (R)-2-((tert-butoxycarbonyl)amino)-2-(3,5-dichloro-4-hydroxyphenyl)acetic acid 
• 1027761-55-2 (R)-2-(((9H-fluoren-9-yl)-methoxy)carbonylamino)-2-(3,5-dichloro-4-hydroxyphenyl)acetic acid 
• 872877-33-3 2-benzyloxycarbonylamino-3-[6-(5-{[2-tert-butoxycarbonylamino-2-(3,5-dichloro-4-hydroxy-phenyl)-acetylamino]-methoxycarbonyl-methyl}-3-iodo-2-methoxy-phenyl)-1H-indol-3-yl]-propionic acid tert-butyl ester 
• 872876-83-0 (R,R)-(6'-iodo-N-carbobenzyloxytryptophyl)-3',5'-dichloro-4'-hydroxyphenylglycine tert-butyl ester 
• 872877-10-6 (R,R)-N-tert-butoxycarbonyl-3',5'-dichloro-4'-hydroxyphenylglycyl-4'-hydroxy-3',5'-diiodophenylglycine methyl ester 
• 872877-12-8 (R,R)-N-tert-butoxycarbonyl-3',5'-dichloro-4'-methoxyphenylglycyl-3',5'-diiodo-4'-methoxyphenylglycine methyl ester 
• 872876-81-8 (R)-3',5'-dichloro-4'-hydroxyphenylglycine tert-butyl ester 

Relevant articles and documents

STRUCTURE OF COMPLESTATIN, A VERY STRONG INHIBITOR OF PROTEASE ACTIVITY OF COMPLEMENT IN THE HUMAN COMPLEMENT SYSTEM

The structure of complestatin, which strongly inhibits the protease activity of complements in the human complement system, has been determined as shown in Fig.2 mainly based on HMBC.Its structure is closely related to glycopeptide antibiotics.

Synthesis of linear tripeptides for right-hand segments of complestatin

This paper concerns a synthetic study of the right-hand segment of complestatin, an inhibitor of gp120-CD4 receptor. The effective synthesis of four important precursors for the right-hand segment of complestatin is described. Two of them are the precurso