257-05-6Relevant articles and documents
Three-step synthesis of (thio)xanthene and dibenzothiepine/dibenzoxepine by an intramolecular Mizoroki-Heck reaction of diaryl (thio)ethers
Jepsen, Tue Heesgaard,Larsen, Mogens,J?rgensen, Morten,Nielsen, Mogens Br?ndsted
, p. 418 - 422 (2012/03/11)
We present a novel three-step protocol for preparing xanthene/thioxanthene and dibenzothiepine/dibenzoxepine from readily available starting materials. The Mizoroki-Heck cyclization as the final step was optimized to afford full conversion of the corresponding diaryl (thio)ethers and furthermore to achieve reasonably good selectivity between the 6-exo and the 7-endo products. Georg Thieme Verlag Stuttgart · New York.