2570-01-6

Basic information

• Product Name: 2,3-diphenylcycloprop-2-ene-1-thione
• Synonyms: 2,3-Diphenylcycloprop-2-ene-1-thione; 2-Cyclopropen-1-thione, 2,3-diphenyl-; 2-cyclopropene-1-thione, 2,3-diphenyl-
• CAS NO: 2570-01-6
• Molecular Formula: C₁₅H₁₀S
• Molecular Weight: 222.3049
• Mol File: 2570-01-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 127-128 °C(Solv: cyclohexane (110-82-7))
• Boiling Point: 373.6°C at 760 mmHg
• Flash Point: 179.8°C
• Density: 1.24g/cm³
• Vapor Pressure: 1.9E-05mmHg at 25°C
• Refractive Index: 1.708
• CAS DataBase Reference: 2,3-diphenylcycloprop-2-ene-1-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-diphenylcycloprop-2-ene-1-thione(2570-01-6)
• EPA Substance Registry System: 2,3-diphenylcycloprop-2-ene-1-thione(2570-01-6)

Safety Data

• Hazardous Substances Data: 2570-01-6(Hazardous Substances Data)

Usage

Main properties

1. Chemical compound belonging to the class of cyclopropenes
2. Thione derivative of cyclopropene
3. Contains two phenyl groups attached to the cyclopropene ring
4. Potential applications in pharmaceuticals, agrochemicals, and materials science
5. Uses in organic synthesis and as a building block for new functional molecules
6. Unique structure and properties make it of interest to researchers

Specific content

Belongs to the class of cyclopropenes
Thione derivative with two phenyl groups attached
Potential applications in pharmaceuticals, agrochemicals, and materials science
Can be used in organic synthesis and as a building block for new molecules
Of interest to researchers for its potential utility in various chemical and biological processes

Upstream product

• 71-43-2 benzene 
• 77853-19-1 C₂₉H₂₀O₂S₂ 
• 886-38-4 diphenylcyclopropenone 
• 77853-17-9 3,3-Bis-1,2-diphenylcyclopropene 
• 2570-00-5 3,3-dichloro-1,2-diphenylcyclopropene 

Downstream Products

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• 108201-04-3 2-(t-Butylthio)-3,4-diphenyl-7,11b-dihydro-2H,6H-<1.3>thiazino<2.3-a>isochinolin 
• 108201-05-4 2-(t-Butylthio)-11b-methyl-3,4-diphenyl-7,11b-dihydro-2H,6H-<1.3>thiazino<2.3-a>isochinolin 
• 71611-94-4 10b-Methyl-2,3-diphenyl-1-thioxo-1,5,6,10b-tetrahydropyrrolo<2.1-a>isochinolin 
• 77022-28-7 6-ethoxy-5-ethoxycarbonyl-3,4-diphenylthiopyran-2-one 
• 603-35-0 triphenylphosphine 
• 108201-02-1 10b-Methyl-2,3-diphenyl-1-thioxo-1,5,6,10b-tetrahydro-7,8-benzopyrrolo<2.1-a>isochinolin 
• 71612-02-7 11b-Isopropyl-2-methoxy-3,4-diphenyl-7,11b-dihydro-2H,6H-<1.3>thiazino<2.3-a>isochinolin 
• 71612-03-8 11b-benzyl-2-methoxy-3,4-diphenyl-7,11b-dihydro-2H,6H-[1,3]thiazino[2,3-a]isoquinoline 
• 71612-00-5 11b-Methyl-2-ethoxy-3,4-diphenyl-7,11b-dihydro-2H,6H-<1.3>thiazino<2.3-a>isochinolin 
• 71611-99-9 2-Methoxy-11b-methyl-3,4-diphenyl-7,11b-dihydro-2H,6H-<1.3>thiazino<2.3-a>isochinolin 
• 53344-50-6 3,3a-diphenyl-2-thioxo-octahydro-spiro[benzo[1,3]cyclopropa[1,2-b]pyrrolium-1,4'-morpholinium] betaine 
• 13232-76-3 4,5-diphenyl-[1,2]dithiole-3-thione 

Relevant articles and documents

Reactions of cyclopropenethiones and acetylenedicarboxylates: Synthesis of substituted thioethers and thiocyclobutanones

The reaction of cyclopropenethiones and electron-deficient alkynes has been described in this context. The corresponding thioethers and thiocyclobutanones were afforded depending on the reaction conditions and the employed substrates. Ambient water partic

Synthesis, characterization, and oxidation electrochemistry of some novel 1,2-dithiol-3-ones and 1,2-dithiol-3-thiones containing aryl and metallocenyl fragments

A new synthesis method was established for 1,2-dithiol-3-ones and 1,2-dithiol-3-thiones, from different cyclopropenones: diphenyl (a), bis-(4-methoxyphenyl (b), diferrocenyl (c) and diruthenocenyl (d), in the presence of elemental sulfur with yields of the 5a-d (35–57%), or in the presence of the additive NaHS, with yields of the 5a-d (45–72%) and 6a-d (10–18%). The characterization of the new compounds was conducted by IR, 1H and 13C NMR spectroscopy, elemental analysis, mass-spectrometry. In addition, X-ray crystallographic analysis of the compounds 5a,b,d was conducted. The redox properties of the heterocyclic compounds were investigated using cyclic (CV), differential pulse (DPV) and square wave (SWV) voltammetries.

A Cyclopropenethione-Phosphine Ligation for Rapid Biomolecule Labeling

Cyclopropenethiones are reported as new bioorthogonal reagents. These motifs react readily with substituted phosphines to provide thiocarbonyl adducts. In some cases, the ligations are >300-fold faster than analogous reactions with bioorthogonal cyclopropenones. Dialkyl cyclopropenethiones are also stable in aqueous buffers and can be used for biomolecule labeling in vitro and in cell lysate. The rapid reactivity and biocompatibility of cyclopropenethiones suggest that they will be useful probes for cellular studies.