2570-32-3

Basic information

• Product Name: 2′-hydroxy-3′-methoxyflavone
• Synonyms: 2′-hydroxy-3′-methoxyflavone
• CAS NO: 2570-32-3
• Molecular Weight: 268.269
• Mol File: 2570-32-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2′-hydroxy-3′-methoxyflavone(CAS DataBase Reference)
• NIST Chemistry Reference: 2′-hydroxy-3′-methoxyflavone(2570-32-3)
• EPA Substance Registry System: 2′-hydroxy-3′-methoxyflavone(2570-32-3)

Safety Data

• Hazardous Substances Data: 2570-32-3(Hazardous Substances Data)

Upstream product

• 289636-11-9 2-benzyloxy-2'-hydroxy-3-methoxy-chalcone 
• 2011-06-5 2-benzyloxy-3-methoxybenzaldehyde 
• 2554-84-9 2',3'-Dimethoxyflavone 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 

Relevant articles and documents

Synthesis and anti-platelet, anti-inflammatory and anti- allergic activities of methoxyisoflavanquinone and related compounds

In a continuation of our search for novel anti-platelet agents, isoflavone quinone and isoflavanquinone were selected as lead compounds and the synthesis of their methoxy derivatives was carried out. Among them, the 4'- and 7-methoxy derivatives were successfully prepared, whereas the attempt to obtain 3'-methoxy derivatives resulted in their isomers, 3'-methoxyflavone quinone and 3'-methoxyflavanquinone, instead. After screening for their anti-platelet, anti-inflammatory and anti-allergic activities, a preliminary structure-activity relationship was established. Compounds 6c, 7a - c, 8c and 9a - c were found to exhibit significant activities. In particular, compound 7c demonstrated very potent anti-platelet, anti-inflammatory and anti-allergic activities and was then recommended for further pharmacological investigation.