257293-27-9Relevant academic research and scientific papers
Disubstituted indazoles as potent antagonists of the integrin α(v)β3
Batt, Douglas G.,Harlow, Patricia P.,Barbera, Frank A.,Spitz, Susan M.,Wexler, Ruth R.,Jadhav, Prabhakar K.,Petraitis, Joseph J.,Houghton, Gregory C.,Modi, Dilip P.,Cain, Gary A.,Corjay, Martha H.,Mousa, Shaker A.,Bouchard, Peter J.,Forsythe, Mark S.
, p. 41 - 58 (2007/10/03)
A new series of indazole-containing α(v)β3 integrin antagonists is described. Starting with lead compound 18a, variations in a number of structural features were explored with respect to inhibition of the binding of β3-transfected 29
