257300-01-9

Upstream product

• 78906-15-7 tert-butyldimethylsilyl (S)-glycidyl ether 
• 7051-16-3 1-chloro-3,5-dimethoxybenzene 

Downstream Products

• 257300-00-8 2-Diphenylphosphanyl-benzoic acid (1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl ester 
• 257299-99-3 C₃₂H₃₃INO₅PS 
• 257299-94-8 (1R,3S)-5-Iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-3-triisopropylsilanyloxymethyl-1,2,3,4-tetrahydro-isoquinoline 
• 257300-03-1 (1R,3S)-6,8-Dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-3-triisopropylsilanyloxymethyl-1,2,3,4-tetrahydro-isoquinoline 
• 257299-95-9 [(1R,3S)-5-Iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-methanol 
• 257300-02-0 N-[2-(tert-butyl-dimethyl-silanyloxy)-1-(3,5-dimethoxy-benzyl)-ethyl]-acetamide 
• 228704-10-7 2-(tert-butyl-dimethyl-silanyloxy)-1-(3,5-dimethoxy-benzyl)-ethylamine 

Relevant academic research and scientific papers

A stereospecific, intermolecular biaryl-coupling approach to korupensamine A en route to the michellamines

By what means and how well can axial chirality be controlled in an intermolecular Suzuki biaryl cross-coupling reaction? The directionality of reductive elimination [Eq.(1)] is completely controlled by using a strategically positioned internal ligand L to afford a single biaryl atropisomer corresponding to the korupensamine A skeleton. TIPS = iPr3Si, Ts = H3CC6H4SO2.