257627-71-7

Upstream product

• 257627-70-6 (2S,3S,4S,5R)-1-(4-dimethylphenylsilyl-5-hydroxymethyl-2,3,5-trimethyltetra-hydrofuran-3-yl)ethanone 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 257627-73-9 benzoic acid (1R,2R,5S,7S,8S)-2-methoxy-1,2,5,7-tetramethyl-3,6-dioxabicyclo-[3.2.1]oct-8-yl ester 
• 257627-74-0 benzoic acid (2R,3R,4R,5S)-4-hydroxy-2-hydroxymethyl-2,4,5-trimethyltetra-hydrofuran-3-yl ester 
• 257627-77-3 benzoic acid (1S,4S,6S,7S)-3-hydroxy-1,4,6-trimethyl-2,5-dioxabicyclo[2.2.1]hept-7-yl ester 
• 257627-76-2 benzoic acid (1S,3S,4R,7S)-1,3,4-trimethyl-6-oxo-2,5-dioxabicyclo[2.2.1]hept-7-yl ester 

Relevant academic research and scientific papers

Stereoselection in the prins-pinacol synthesis of 2,2-disubstituted 4-acyltetrahydrofurans. Enantioselective synthesis of (-)-citreoviral.

[reaction: see text] The condensation of allylic diols with unsymmetrical ketones proceeds with high stereoselection to form 2,2-disubstituted 4-acyltetrahydrofurans when the alpha-substituents of the ketone differ substantially in size. A Prins-pinacol c