25765-10-0Relevant academic research and scientific papers
Kinetics and mechanism of transaldimination of amino acids and aromatic amines with pyridoxal
Pishchugin,Tuleberdiev
, (2013)
Kinetics and mechanism of transaldimination of amino acids and aromatic amines with pyridoxal have been studied by means of UV spectroscopy and polarimetry. It has been shown that aminal intermediates are formed in reaction of the Schiff's bases with p-am
Transition-state analogues as inhibitors for GABA-aminotransferase
Iskander, MN,Andrews, PR,Winkler, DA,Brinkworth, RI,Paola, C Di,et al.
, p. 129 - 136 (2007/10/02)
Our previous calculations on the reaction catalysed by GABA-aminotransferase (GABA-T) have been utilized in this work in order to synthesize a series of reversible inhibitors of this enzyme.The synthesized transition-state analogues and their precursors i
