25765-12-2Relevant academic research and scientific papers
Schiff base Sn(IV) complexes as cytotoxic agents: Synthesis, structure, isosteric and bioisosteric replacement
Galván-Hidalgo, José M.,Ramírez-Apan, Teresa,Nieto-Camacho, Antonio,Hernández-Ortega, Simón,Gómez, Elizabeth
, p. 332 - 343 (2017)
The preparation and characterization of two series of organotin(IV) complexes are reported, each series differing in the nature of the substituent bonded to the tin atom (cyclohexyl or bis(trimethyl)silylmethyl). The isosteric and bioisosteric approach wa
Bioactive penta-coordinated diorganotin(Iv) complexes of pyridoxalimine schiff bases
Asijaa, Sonika,Malhotra, Nidhi,Malhotra, Rajeh
, p. 1510 - 1520,11 (2020/08/24)
Diorganotin(IV) complexes of an extended system derived from the condensation of pyridoxal hydrochloride with 2-amino phenol (H2L1), 2-amino-4-methyl phenol (H2L2), 2-amino-4-chloro phenol (H2L 3), 2-amino-4-nitro phenol (H2L4), 1-amino-2-naphthol hydrochloride (H2L5) have been synthesized by the reaction of dichlorodiorganotin(IV) in a 1:1 molar ratio with these ligands. Spectral studies (IR, 1H, 13C, 119Sn NMR) along with physical data evidenced the formation of penta-coordinated species with the ligands acting as tridentate (ONO) with oxygen occupying the axial positions, and nitrogen at one of the equatorial positions. The ligands and their organotin complexes have been evaluated for antimicrobial activity against phytopathogenic fungi Candida albicans and Aspergillus niger at 25 1C and bacteria Bacillus subtilis, Escherichia coli, and Staphylococcus aureus at 37 1C. The activities of the ligands have been enhanced on complexation and the results indicate that they exhibit significant antimicrobial properties. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.
