25771-84-0 Usage
General Description
3,8-Dichloroquinolin-4-ol is a chemical compound with the molecular formula C9H5Cl2NO. It is a derivative of quinoline and contains two chlorine atoms. 3,8-DICHLOROQUINOLIN-4-OL has been studied for its potential use as an antimicrobial agent due to its ability to inhibit the growth of certain bacteria and fungi. It has also been investigated for its potential as an anti-cancer agent, with some studies showing promising results in inhibiting the growth of cancer cells. Its unique structure and potential biological activities make 3,8-Dichloroquinolin-4-ol an interesting compound for further research and development in various fields of pharmaceutical and medical science.
Check Digit Verification of cas no
The CAS Registry Mumber 25771-84-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,7 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25771-84:
(7*2)+(6*5)+(5*7)+(4*7)+(3*1)+(2*8)+(1*4)=130
130 % 10 = 0
So 25771-84-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H5Cl2NO/c10-6-3-1-2-5-8(6)12-4-7(11)9(5)13/h1-4H,(H,12,13)
25771-84-0Relevant articles and documents
Cyclisation reactions of some pyridazinylimidoylketenes
Gaywood, Alexander P.,Hill, Lawrence,Imam, S. Haider,McNab, Hamish,Neumajer, Gabor,O'Neill, William J.,Matyus, Peter
experimental part, p. 236 - 242 (2010/06/13)
Flash vacuum pyrolysis (FVP) of aminopyridazinone derivatives of Meldrum's acid at 600 °C (0.02 Torr) results in generation of an imidoylketene intermediate followed by cyclisation. In the case of the 5-amino derivatives, the products are pyrido[2,3-d]pyridazines, whereas the 4-amino compounds lead to mixtures of pyrido[2,3-d]pyridazines and pyrrolo[3,2-c]pyridazines. The feasibility of the 1,5-sigmatropic shift of a chlorine atom, required for the formation of two of the pyrido[2,3-d]pyridazines, was supported by the corresponding reaction of a corresponding 2,6-dichloroaniline derivative. The feasibility of the decarboxylation mechanism required for the formation of the pyrrolo[3,2-c]pyridazines, was supported by related processes in the FVP reactions of model compounds and by DFT calculations.
