25771-89-5 Usage
General Description
6,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid ethyl ester is a chemical compound characterized by the presence of a quinoline backbone, which is a nitrogen-containing heterocyclic compound. Its structure is further modified by the presence of two chlorine atoms, a hydroxy group, a carboxylic acid ethyl ester group attached to different positions on the quinoline ring. Although precise information about its use is not commonly available, it is widely acknowledged that compounds with a quinoline structure can possess important biological activities such as antibacterial, antifungal, anticancer, and anti-inflammatory effects; hence, the compound may have potential medicinal applications. The compound's physicochemical properties go hand in hand with its structure, and may vary according to a variety of conditions such as temperature and pH.
Check Digit Verification of cas no
The CAS Registry Mumber 25771-89-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,7 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 25771-89:
(7*2)+(6*5)+(5*7)+(4*7)+(3*1)+(2*8)+(1*9)=135
135 % 10 = 5
So 25771-89-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H9Cl2NO3/c1-2-18-12(17)8-5-15-10-7(11(8)16)3-6(13)4-9(10)14/h3-5H,2H2,1H3,(H,15,16)
25771-89-5Relevant articles and documents
Dichloro-4-quinolinol-3-carboxylic acid: Synthesis and antioxidant abilities to scavenge radicals and to protect methyl linoleate and DNA
Li, Guo-Xiang,Liu, Zai-Qun,Luo, Xu-Yang
experimental part, p. 1821 - 1827 (2010/06/21)
5,7-, 5,8-, 6,8-, 7,8-Dichloro-4-quinolinol-3-carboxylic acid (5,7-, 5,8-, 6,8-, 7,8-DCQA) together with 7-chloro-4-quinolinol-3-carboxylic acid (7-CQA) and 4-quinolinol-3-carboxylic acid (QA) were synthesized to investigate the antioxidant properties. 5,7-DCQA exhibited the highest ability to scavenge 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate) cationic radical (ABTS+.), 2,2′-diphenyl-1-picrylhydrazyl (DPPH) and galvinoxyl radicals. 6,8-DCQA possessed the highest efficacy to protect methyl linoleate against 2,2′-azobis(2-amidinopropane)dihydrochloride (AAPH)-induced oxidation. 5,7-, 5,8-DCQA and QA were able to retard the β-carotene-bleaching in β-carotene-linoleic acid emulsion. In addition, 5,8- and 6,8-DCQA efficiently protected DNA against hydroxyl radical (.OH)-mediated oxidation, and 5,8-DCQA and 7-CQA were active to protect DNA against AAPH-induced oxidation. Furthermore, only 7-CQA can protect DNA against Cu2+/glutathione (GSH)-mediated oxidation. Dichloro-4-quinolinol-3-carboxylic acids were potent to be antiradical drugs, and were worthy to be researched pharmacologically.
