25772-81-0

Basic information

• Product Name: 2-Propanol, 1-chloro-3-(2-methoxyphenoxy)-
• CAS NO: 25772-81-0
• Molecular Formula: C10H13ClO3
• Molecular Weight: 216.664
• Mol File: 25772-81-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Propanol, 1-chloro-3-(2-methoxyphenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanol, 1-chloro-3-(2-methoxyphenoxy)-(25772-81-0)
• EPA Substance Registry System: 2-Propanol, 1-chloro-3-(2-methoxyphenoxy)-(25772-81-0)

Safety Data

• Hazardous Substances Data: 25772-81-0(Hazardous Substances Data)

Upstream product

• 96-23-1 1,3-Dichloro-2-propanol 
• 5633-98-7 potassium guaiacolate 
• 13052-77-2 sodium 2-methoxyphenolate 
• 90-05-1 2-methoxy-phenol 
• 106-89-8 epichlorohydrin 
• 2210-74-4 2-(2-methoxy-phenoxymethyl)-oxirane 

Downstream Products

• 10415-15-3 1-(3-Allyloxy-2-hydroxy-propylamino)-3-(2-methoxy-phenoxy)-propan-2-ol 
• 126891-79-0 3-(2-methoxyphenoxy)-1-phthalimido-2-propanol 
• 70-07-5 mephenoxalone 
• 91520-01-3 3,4-dihydro-3-hydroxy-8-methoxy-2H-1-benzopyran 
• 141987-28-2 1-chloro-3-(2-methoxyphenoxy)propan-2-yl acetate 
• 95635-55-5 Ranolazine 
• 63257-76-1 1-(2-Methoxyphenoxy)-2-oxy-3-aminopropane 
• 153756-96-8 4-acetamidophenyl N-<3-(2-methoxyphenoxy)-2-hydroxypropyl>carbamate 
• 5741-22-0 moprolol 
• 141987-38-4 (S)-1-chloro-3-(2-methoxyphenoxy)-2-propanol 
• 141987-47-5 (R)-1-chloro-3-(2-methoxyphenoxy)-2-propanol 
• 77164-20-6 (2S)-1-(isopropylamino)-3-(2-methoxyphenoxy)propan-2-ol 
• 61248-99-5 (S)-1,2-epoxy-3-(2-methoxyphenyloxy)-propane 
• 142036-91-7 Acetic acid (R)-1-chloromethyl-2-(2-methoxy-phenoxy)-ethyl ester 

Relevant articles and documents

Preparation method of methocarbamol beta isomer

The invention provides a preparation method of a methocarbamol beta isomer. According to the preparation method, a 2-((Methoxyphenoxy)methyl)ethylene oxide compound 1 is taken as a starting raw material and is sequentially subjected to chlorination, ester

An efficient synthesis of 1-(2-Methoxyphenoxy)-2,3-epoxypropane: Key intermediate of β-adrenoblockers

An efficient process for the preparation of 1-(2-methoxyphenoxy)-2,3- epoxypropane, a key intermediate for the synthesis of ranolazine is described.

Improvement and simplification of synthesis of 3-aryloxy-1,2-epoxypropanes using solvent-free conditions and microwave irradiations. Relation with medium effects and reaction mechanism

Some 3-aryloxy-1,2-epoxypropanes, interesting as potential synthons in β-adrenergic receptor antagonists preparation, were obtained in excellent yields (65-96% within 2-17 min) by microwave activation (monomode system) using solid-liquid solvent-free phase transfer catalysis (PTC). The best results for the O-alkylation of some phenols with epichlorohydrin were obtained using TBAB and NaOH/K2CO3 (1:4 mol/mol) as phase transfer catalyst and more acceptable basic system, respectively. These new procedure is compared with classical methods. Significant specific microwave effect (non-purely thermal) was evidenced in all cases. They were discussed in terms of reaction medium and mechanism, taking into account the variations in polarity of the systems.