25785-10-8

Basic information

• Product Name: ETHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE
• Synonyms: ETHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE;CBI-BB ZERO/004990;benzo[b]thiophene-2-carboxylic acid, 5-amino-, ethyl ester;5-Amino-Benzo[b]Thiophene-2-Carboxylicacid Ethyl Ester;5-amino-2-benzothiophenecarboxylic acid ethyl ester;5-aminobenzothiophene-2-carboxylic acid ethyl ester;ethyl 5-aminobenzothiophene-2-carboxylate
• CAS NO: 25785-10-8
• Molecular Formula: C₁₁H₁₁NO₂S
• Molecular Weight: 221.28
• Mol File: 25785-10-8.mol
• Article Data: 15

Chemical Properties

• Melting Point: 92-95°C
• Boiling Point: 391.5 °C at 760 mmHg
• Flash Point: 190.6 °C
• Appearance: /
• Density: 1.303g/cm³
• Vapor Pressure: 2.46E-06mmHg at 25°C
• Refractive Index: 1.666
• Storage Temp.: 2-8°C
• PKA: 3.55±0.10(Predicted)
• CAS DataBase Reference: ETHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE(25785-10-8)
• EPA Substance Registry System: ETHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE(25785-10-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 25785-10-8(Hazardous Substances Data)

Usage

General Description

Ethyl 5-amino-1-benzothiophene-2-carboxylate is a chemical compound with a molecular formula C12H13NO2S. It is a synthetic intermediate used in the pharmaceutical industry for the production of various drugs and organic compounds. ETHYL 5-AMINO-1-BENZOTHIOPHENE-2-CARBOXYLATE is a derivative of benzothiophene, which is a heterocyclic aromatic compound containing a sulfur atom in its ring structure. Ethyl 5-amino-1-benzothiophene-2-carboxylate has potential applications in drug discovery and development, particularly in the synthesis of novel therapeutics for various medical conditions. Its chemical structure and properties make it a valuable building block for the creation of complex organic molecules with potential pharmaceutical applications.

InChI:InChI=1/C11H11NO2S/c1-2-14-11(13)10-6-7-5-8(12)3-4-9(7)15-10/h3-6H,2,12H2,1H3

Upstream product

• 6361-21-3 2-chloro-5-nitrobenzaldehyde 
• 25785-09-5 ethyl 5-nitro-2-benzo[b]thiophenecarboxylate 
• 7440-44-0 pyrographite 

Downstream Products

• 850073-46-0 5-dibenzylamino-benzo[b]thiophene-2-carboxylic acid hydroxyamide 
• 1431881-41-2 ethyl 2,3-diphenyl-2H-thieno[2',3':5,6]benzo[1,2-b][1,4]-thiazine-8-carboxylate 
• 1431881-40-1 ethyl 2-methyl-3-phenyl-2H-thieno[2',3':5,6]benzo[1,2-b]-[1,4]thiazine-8-carboxylate 
• 1431881-39-8 ethyl 3-phenyl-2H-thieno[2',3':5,6]benzo[1,2-b][1,4]thiazine-8-carboxylate 
• 1431881-38-7 ethyl 3-(4-bromophenyl)-2H-thieno[2',3':5,6]benzo[1,2-b][1,4]-thiazine-8-carboxylate 
• 1431881-37-6 ethyl 8-methyl-10-phenyl-10H-pyrazolo[4,3-f]thieno[2',3':5,6]-benzo[1,2-b][1,4]thiazepine-2-carboxylate 
• 1431881-36-5 ethyl 2-(4-cyanophenyl)-4-(2-methoxyphenyl)-2,3-dihydro-thieno[2',3':5,6]benzo[1,2-b][1,4]thiazepine-9-carboxylate 
• 1431881-35-4 ethyl 2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-2,3-dihydro-thieno[2',3':5,6]benzo[1,2-b][1,4]thiazepine-9-carboxylate 
• 1431881-34-3 ethyl 4-(4-chlorophenyl)-2-(4-fluorophenyl)-2,3-dihydrothieno-[2',3':5,6]benzo[1,2-b][1,4]thiazepine-9-carboxylate 
• 1431881-33-2 ethyl 2-(4-fluorophenyl)-4-(4-methoxyphenyl)-2,3-dihydro-thieno[2',3':5,6]benzo[1,2-b][1,4]thiazepine-9-carboxylate 
• 1431881-32-1 ethyl 2,4-diphenyl-2,3-dihydrothieno[2',3':5,6]benzo[1,2-b][1,4]thiazepine-9-carboxylate 
• 1431881-31-0 ethyl 5-amino-4-((1-(2-chlorophenyl)-3-(2-hydroxyphenyl)-3-oxopropyl)sulfanyl)benzo[b]thiophene-2-carboxylate 
• 1431881-30-9 ethyl 5-amino-4-((3-(4-chlorophenyl)-1-(4-fluorophenyl)-3-oxopropyl)sulfanyl)benzo[b]thiophene-2-carboxylate 
• 1431881-29-6 ethyl 5-amino-4-((1-(4-fluorophenyl)-3-(4-methoxyphenyl)-3-oxopropyl)sulfanyl)benzo[b]thiophene-2-carboxylate 

Relevant articles and documents

Benzo[b]thiophene-based histone deacetylase inhibitors

Benzo[b]thienyl hydroxamic acids, a novel class of histone deacetylase (HDAC) inhibitors, were identified via a targeted screen of small molecule hydroxamic acids. Various substitutions were explored in the C5- and C6-positions of the benzo[b]thiophene co

Inhibitors of soluble adenylate cyclase

The invention relates to compounds of general Formula I, the production thereof, and the use thereof as a medicinal product.

BENZOTHIOPHENE HYDROXAMIC ACID DERIVATIVES WITH CARBAMATE, UREA, AMIDE AND SULFONAMIDE SUBSTITUTIONS

The present invention relates to a novel class of hydroxamic acid derivatives carbamate, urea, amide and sulfonamide substitutions. The hydroxamic acid compounds can be used to treat cancer. The hydroxamic acid compounds can also inhibit histone deacetyla