25785-60-8

Basic information

• Product Name: 2,5-dicyclohexylbenzene-1,4-diol
• Synonyms: 1,4-benzenediol, 2,5-dicyclohexyl-; 2,5-Dicyclohexylbenzene-1,4-diol
• CAS NO: 25785-60-8
• Molecular Formula: C₁₈H₂₆O₂
• Molecular Weight: 274.3978
• Mol File: 25785-60-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 363.2°C at 760 mmHg
• Flash Point: 160.3°C
• Density: 1.103g/cm³
• Vapor Pressure: 8.75E-06mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 2,5-dicyclohexylbenzene-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dicyclohexylbenzene-1,4-diol(25785-60-8)
• EPA Substance Registry System: 2,5-dicyclohexylbenzene-1,4-diol(25785-60-8)

Safety Data

• Hazardous Substances Data: 25785-60-8(Hazardous Substances Data)

Usage

Physical State

White crystalline solid

Molecular Weight

298.42 g/mol

Main Uses

Production of UV absorbers and stabilizers for plastics and polymers
Synthesis of pharmaceuticals and organic compounds

Special Properties

Potential antioxidant properties
Ability to inhibit the growth of certain bacteria and fungi

Research Potential

Potential as a building block in developing new materials and bioactive compounds

Upstream product

• 123-31-9 hydroquinone 
• 110-83-8 cyclohexene 
• 108-93-0 cyclohexanol 
• 1207096-42-1 2,5-di(cyclohex-1-en-3-yl)benzene-1,4-diol 

Downstream Products

• 859033-21-9 1,3,4-triacetoxy-2,5-dicyclohexyl-benzene 
• 109692-69-5 2,5-dicyclohexyl-3-hydroxy-[1,4]benzoquinone 
• 859033-22-0 3,6-dicyclohexyl-benzene-1,2,4-triol 
• 102957-87-9 1,4-diacetoxy-2,5-dicyclohexyl-benzene 

Relevant articles and documents

Synthesis and inhibitory evaluation of cyclohexen-2-yl- and cyclohexyl-substituted phenols and quinones to endothelial cell and cancer cells

Alkylation of phenols with 1,3-cyclohexadiene (1) has been conducted and a series of cyclohexen-2-yl- and cyclohexyl-substituted phenols and quinones were screened against the proliferation of HUVEC and cancer cells. Phenol type as well as the size and occupied position of the substitute are important for the alkylating reaction and the inhibitory activity and selectivity of a compound. 2,5-Di(cyclohexen-2-yl)benzene-1,4-diol (25) bearing two cyclohexen-2-yl groups and 2-tert-butyl-5-(cyclohexen-2-yl)benzene-1,4-diol (30) bearing cyclohexen-2-yl and tert-butyl groups exhibited good selectivity against HUVEC proliferation (IC50s of 2.0 and 1.4?μM, respectively) with relatively low toxicity to ccc-HPF-1.