257882-02-3Relevant academic research and scientific papers
Efficient synthesis of syn-aziridino alcohols by chelation-controlled addition of dialkylzincs and Grignard reagents to N-benzylaziridino aldehydes
Andres, Jose M.,De Elena, Noemi,Pedrosa, Rafael,Perez-Encabo, Alfonso
, p. 14137 - 14144 (2007/10/03)
N-Benzyl aziridino aldehydes, derived from (L)-sexine and (L)-threonine react with dialkylzinc and alkylmagnesium halides leading to syn-aziridino alcohols as single or major stereoisomers. The diastereoselectivity is affected by the nature of the organometallic and the solvent system.
