257883-22-0 Usage
Chemical Properties
Pale Yellow Solid
Check Digit Verification of cas no
The CAS Registry Mumber 257883-22-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,7,8,8 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 257883-22:
(8*2)+(7*5)+(6*7)+(5*8)+(4*8)+(3*3)+(2*2)+(1*2)=180
180 % 10 = 0
So 257883-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H19N3O4S/c1-21(16-7-4-13(22)11-19-16)8-9-25-14-5-2-12(3-6-14)10-15-17(23)20-18(24)26-15/h2-7,11,15,22H,8-10H2,1H3,(H,20,23,24)
257883-22-0Relevant articles and documents
Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5
Kaspera, Ruediger,Naraharisetti, Suresh B.,Evangelista, Eric A.,Marciante, Kristin D.,Psaty, Bruce M.,Totah, Rheem A.
body text, p. 681 - 691 (2012/03/26)
Genetic polymorphisms in CYP2C8 can influence the metabolism of important therapeutic agents and cause interindividual variation in drug response and toxicity. The significance of the variant CYP2C8*3 has been controversial with reports of higher in vivo
