25790-35-6

Basic information

• Product Name: 1-(2-FURYL)-1,3-BUTANEDIONE
• Synonyms: 1-(2-FURYL)-2,3-BUTANEDIONE;1-(2-FURYL)-1,3-BUTANEDIONE;2-FUROYLACETONE;1-(2-furanyl)-3-butanedione;1-(2-furyl)butane-1,3-dione;1,3-Butanedione, 1-(2-furanyl)-;1-(2-FURYL)-1,3-BUTANEDIONE 96%;1-(2-Furanyl)-1,3-butanedione
• CAS NO: 25790-35-6
• Molecular Formula: C₈H₈O₃
• Molecular Weight: 152.15
• EINECS: 247-265-0
• Product Categories: Miscellaneous
• Mol File: 25790-35-6.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 98 °C (5 mmHg)
• Flash Point: 84-86°C/1mm
• Appearance: Clear yellow to orange-brown/Liquid After Melting
• Density: 1.1677 (rough estimate)
• Vapor Pressure: 0.00118mmHg at 25°C
• Refractive Index: 1.5735-1.5755
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.57±0.23(Predicted)
• CAS DataBase Reference: 1-(2-FURYL)-1,3-BUTANEDIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-FURYL)-1,3-BUTANEDIONE(25790-35-6)
• EPA Substance Registry System: 1-(2-FURYL)-1,3-BUTANEDIONE(25790-35-6)

Safety Data

• Statements: 36/37/38-36
• Safety Statements: 24/25-26
• TSCA: Yes
• Hazardous Substances Data: 25790-35-6(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow to orange-brown liquid after melting

InChI:InChI=1/C8H8O3/c1-6(9)5-7(10)8-3-2-4-11-8/h2-5,10H,1H3

Upstream product

• 614-99-3 Ethyl 2-furoate 
• 138117-37-0 1-(furan-2-yl)-3-hydroxybutan-1-one 
• 67-64-1 acetone 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 79-20-9 acetic acid methyl ester 
• 141-78-6 ethyl acetate 
• 6047-91-2 2-furoyl cyanide 

Downstream Products

• 1192-62-7 1-(2-furyl)-1-ethanone 
• 127-09-3 sodium acetate 
• 141-78-6 ethyl acetate 
• 494831-39-9 [Pd(2,3-(MeO)2C₆H₂CH=N(Cy)-C₆,N)((Ph₂P)2CHCH₂CH(COC₄H₃O-2)(COCH₃)-P,P')]PF₆ 
• 94906-72-6 4-amino-N-(4-furan-2-yl-6-methyl-pyrimidin-2-yl)-benzenesulfonamide 

Relevant articles and documents

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I2-Promoted [3+2] Cyclization of 1,3-Diketones with Potassium Thiocyanate: a Route to Thiazol-2(3H)-One Derivatives

An I2-promoted strategy has been developed for the synthesis of thiazol-2(3H)-one derivatives from 1,3-diketones with potassium thiocyanate. This [3+2] cyclization reaction involves C?S and C?N bond formation and exhibits good functional group tolerance. A series of thiazol-2(3H)-one derivatives are obtained in moderate to good yields. (Figure presented.).

Direct synthesis of 2,3,5-trisubstituted pyrroles: via copper-mediated one-pot multicomponent reaction

We have developed a copper-mediated one-pot synthesis of 2,3,5-trisubstituted pyrroles from 1,3-dicarbonyl compounds and acrylates using ammonium acetate as a nitrogen source. The reaction achieves C-C and C-N bond formation and provides an efficient approach to access highly functionalized pyrroles without further raw material preparation. This method is operationally simple, compatible with a wide range of functional groups, and provides the target products in moderate to good yields. This journal is

A General Proline-Catalyzed Synthesis of 4,5-Disubstituted N-Sulfonyl-1,2,3-Triazoles from 1,3-Dicarbonyl Compounds and Sulfonyl Azide

An efficient proline-catalyzed synthesis of 4,5-disubstituted-N-sulfonyl-1,2,3-triazoles has been accomplished from 1,3-dicarbonyl compounds and sulfonyl azides. The developed reaction is suitable for various symmetrical and unsymmetrical 1,3-dicarbonyl compounds, tolerates various functional groups and affords 4,5-disubstituted-N-sulfonyl-1,2,3-triazoles in good yield with excellent regioselectivity. Rhodium-catalyzed denitrogenative functionalization of 4,5-disubstituted-N-sulfonyl-1,2,3-triazoles further demonstrates their utility in organic synthesis.