257940-60-6

Basic information

• Product Name: 2H-Furo[2,3-b]pyrrole, 6-acetylhexahydro-3-methylene-, (3aR,6aS)-rel- (9CI)
• Synonyms: 2H-Furo[2,3-b]pyrrole, 6-acetylhexahydro-3-methylene-, (3aR,6aS)-rel- (9CI)
• CAS NO: 257940-60-6
• Molecular Formula: C9H13NO2
• Molecular Weight: 167.20502
• Product Categories: ACETYLGROUP
• Mol File: 257940-60-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 305.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.14±0.1 g/cm3(Predicted)
• PKA: -0.21±0.20(Predicted)
• CAS DataBase Reference: 2H-Furo[2,3-b]pyrrole, 6-acetylhexahydro-3-methylene-, (3aR,6aS)-rel- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Furo[2,3-b]pyrrole, 6-acetylhexahydro-3-methylene-, (3aR,6aS)-rel- (9CI)(257940-60-6)
• EPA Substance Registry System: 2H-Furo[2,3-b]pyrrole, 6-acetylhexahydro-3-methylene-, (3aR,6aS)-rel- (9CI)(257940-60-6)

Safety Data

• Hazardous Substances Data: 257940-60-6(Hazardous Substances Data)

Upstream product

• 23105-58-0 N-[(methyl)carbonyl]-2-pyrroline 

Relevant articles and documents

Synthesis of substituted pyrrolidines by sequential radical cyclization and N-acyliminium ion reactions

Readily available N-acyl-2-pyrrolines are converted into functionalized α-alkoxy-β-iodopyrrolidines by N-iodosuccinimide promoted alcohol addition to the enamine group. These compounds are readily cyclized using a sodium cyanoborohydride-catalytic tributylstannane system affording functionalized pyrrolidines in good yields. The cyclized products undergo N-acyliminium ion reactions, such as BF3·OEt2 mediated addition of allyltrimethylsilane.