25796-09-2 Usage
Uses
Used in Pharmaceutical Industry:
17-ethynyl-5-estrane-3,17-diol is used as a pharmaceutical compound for its estrogen receptor agonist activity in osteoblastic cells. This property makes it a potential candidate for the treatment of conditions related to bone health, such as osteoporosis.
Used in Hormonal Regulation:
As a progesterone receptor agonist, 17-ethynyl-5-estrane-3,17-diol is used for hormonal regulation, particularly in the treatment of conditions related to the menstrual cycle, such as dysmenorrhea and endometriosis.
Used in Cardiovascular Applications:
17-ethynyl-5-estrane-3,17-diol is used as a vasorelaxing agent for its novel nongenomic endothelium-independent effects. This application makes it a potential candidate for the treatment of cardiovascular diseases, where vasorelaxation can help improve blood flow and reduce the risk of heart-related complications.
Check Digit Verification of cas no
The CAS Registry Mumber 25796-09-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,9 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 25796-09:
(7*2)+(6*5)+(5*7)+(4*9)+(3*6)+(2*0)+(1*9)=142
142 % 10 = 2
So 25796-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H30O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,13-18,21-22H,4-12H2,2H3/t13-,14-,15+,16-,17-,18+,19+,20?/m1/s1
25796-09-2Relevant academic research and scientific papers
Synthesis of 5β,17α-19-norpregn-20-yne-3β,17-diol and of 5β,17α-19-norpregn-20-yne-3α,17-diol, human metabolites of norethindrone
Curts, Stephen W.,Wren, Douglas L.,Cooper, Gary F.
, p. 8 - 11 (2007/10/02)
A convenient synthesis of both 5β, 17α-19-norpregn-20-yne-3β,17-diol (1) and 5β,17α-19-norpregn-20-yne-3α, 17-diol (2) in multigram quantities from estr-4-ene-3, 17-dione is reported. Full characterization of these often-cited human melaholites of norethindrone is presented for the first time.
