25808-30-4

Basic information

• Product Name: Methylaminoacetonitrile hydrochloride
• Synonyms: MethylaMinoacetonitrile Hydrochloride, 97+%;(methylamino)-acetonitrilmonohydrochloride;SARCOSINE NITRILE HYDROCHLORIDE;SARCOSINITRILE;SARCOSINITRILE HYDROCHLORIDE;ACETONITRILE, (METHYLAMINO)-, MONOHYDROCHLORIDE;METHYLAMINOACETONITRILE HCL;METHYLAMINOACETONITRILE HYDROCHLORIDE
• CAS NO: 25808-30-4
• Molecular Formula: C₃H₆N₂*ClH
• Molecular Weight: 106.55
• EINECS: 247-277-6
• Product Categories: Anthraquinones, Hydroquinones and Quinones;Building Blocks;C1 to C5;Chemical Synthesis;Cyanides/Nitriles;Nitrogen Compounds;Organic Building Blocks
• Mol File: 25808-30-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 103-106 °C(lit.)
• Boiling Point: 150.2ºC at 760 mmHg
• Flash Point: 44.6ºC
• Appearance: /
• Vapor Pressure: 3.89mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• BRN: 3908975
• CAS DataBase Reference: Methylaminoacetonitrile hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Methylaminoacetonitrile hydrochloride(25808-30-4)
• EPA Substance Registry System: Methylaminoacetonitrile hydrochloride(25808-30-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 25808-30-4(Hazardous Substances Data)

Usage

Chemical Properties

Yellow crystal

Uses

Methylaminoacetonitrile hydrochloride can be used as an intermediate in pharmaceutical and chemical synthesis. It is the raw material for the preparation of tadalafil. Approved by the FDA in 2003, tadalafil was marketed in the United States as a drug for the treatment of erectile dysfunction in men.

InChI:InChI=1/C3H6N2.ClH/c1-5-3-2-4;/h5H,3H2,1H3;1H

Downstream Products

• 40511-15-7 1-(3,4-dimethoxy-phenyl)-2-methylamino-ethanone; hydrochloride 
• 117712-19-3 1-(4-methoxy-phenyl)-2-methylamino-ethanone 
• 29705-82-6 1-(2,4-dihydroxy-phenyl)-2-methylamino-ethanone; hydrochloride 
• 22977-89-5 2-chloro-N-cyanomethyl-N-methyl-4-nitrobenzamide 
• 142256-48-2 4-(2-Methylphenyl)-2,6,7-trimethyl-1(2H)-isoquinolinone-3-carboxylic acid 
• 168541-96-6 N-(cyanomethyl)-3-(4-fluorobenzoyl)-N-methyl-2-pyridinecarboxamide 
• 78441-57-3 N-carbophenoxy-N-methylaminoacetonitrile 
• 29705-80-4 1-(4-methoxyphenyl)-2-(methylamino)ethan-1-one hydrochloride 
• 36800-79-0 N-benzoyl-N-methylaminoacetonitrile 
• 136262-88-9 (Cyanomethyl-methyl-amino)-o-tolyl-acetonitrile 
• 135762-90-2 α-[(cyanomethyl)methylamino]benzeneacetonitrile 
• 135737-05-2 (4-Chloro-phenyl)-(cyanomethyl-methyl-amino)-acetonitrile 
• 87486-33-7 3,5-Dichloro-1-methyl-2(1H)-pyrazinone 
• 35118-28-6 N-Cyanomethyl-N-methyl-2-nitro-benzamide 

Relevant articles and documents

METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS

The invention features a method for treating chronic pain using a compound selected from formulae (I), (II)A, (I)B and (I)C.