25812-76-4Relevant academic research and scientific papers
Triazolyl azabicyclo[3.1.0]hexanes: A class of potent and selective dopamine D3 receptor antagonists
Bonanomi, Giorgio,Braggio, Simone,Capelli, Anna Maria,Checchia, Anna,Di Fabio, Romano,Marchioro, Carla,Tarsi, Luca,Tedesco, Giovanna,Terreni, Silvia,Worby, Angela,Heibreder, Christian,Micheli, Fabrizio
experimental part, p. 705 - 715 (2011/01/05)
Herein we report a detailed description of the structure-activity relationships for a novel series of "C-linked" 1,2,4- triazolylazabicyclo[3.1.0]hexanes. These derivatives are endowed with very high in vitro affinity and selectivity for the dopamine Dsu
5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents
Kane,Staeger,Dalton,Miller,Dudley,Ogden,Kehne,Ketteler,McCloskey,Senyah,Chmielewski,Miller
, p. 125 - 132 (2007/10/02)
Selected examples from three series of isomeric (alkylthio)-1,2,4- triazoles were prepared and examined for anticonvulsant activity versus strychnine-, maximal-electroshock-, pentylenetetrazole-, and 3- mercaptopropionic-acid-induced seizures in mice. A n
3-aryl-5-alkylthio-4H-1,2,4-triazoles
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, (2008/06/13)
This invention relates to novel sulfone and sulfoxide derivatives of 3-aryl-5-alkylthio-4H-1,2,4-triazoles and to the use of 3-aryl-5-alkylthio-, alkylsulfinyl- and alkylsulfonyl-4H-1,2,4-triazoles in the treatment of patients suffering from convulsant seizures.
3-aryl-5-alkylthio-4H-1,2,4-traizoles for treatment of hyperreflexia due to spinal trauma
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, (2008/06/13)
This invention relates to the use of 3-aryl-5-alkylthio-4H-1,2,4-triazoles and the corresponding alkylsulfinyl- and alkylsulfonyl-4H-1,2,4-triazoles in the treatment of patients suffering from chronic hyperreflexia due to spinal trauma.
