258278-23-8

Basic information

• Product Name: N,N'-bis(2,4,6-trimethylphenyl)ethane-1,2-diamine,dihydrochloride
• Synonyms: N,N'-bis(2,4,6-trimethylphenyl)ethane-1,2-diamine,dihydrochloride;1,2-Ethanediamine, N,N'-bis(2,4,6-trimethylphenyl)-, dihydrochloride
• CAS NO: 258278-23-8
• Molecular Formula: C₂₀H₂₈N₂*2ClH
• Molecular Weight: 369.3716
• Mol File: 258278-23-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,N'-bis(2,4,6-trimethylphenyl)ethane-1,2-diamine,dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-bis(2,4,6-trimethylphenyl)ethane-1,2-diamine,dihydrochloride(258278-23-8)
• EPA Substance Registry System: N,N'-bis(2,4,6-trimethylphenyl)ethane-1,2-diamine,dihydrochloride(258278-23-8)

Safety Data

• Hazardous Substances Data: 258278-23-8(Hazardous Substances Data)

Upstream product

• 88-05-1 2,4,6-trimethylaniline 
• 56222-36-7 (E,E)-N¹,N²-bis(2,4,6-trimethylphenyl)ethane-1,2-diimine 
• 56222-36-7 N,N'-bis(2,4,6-trimethylphenyl)ethanediimine 

Downstream Products

• 173035-10-4 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazolium chloride 
• 246047-72-3 tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride 
• 134030-21-0 N,N'-dimesityl-1,2-ethanediamine 
• 258278-26-1 1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene 
• 173035-11-5 1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene 
• 260054-47-5 1,3-bis(2,4,6-trimethylphenyl)-2-(trichloromethyl)imidazolidine 

Relevant articles and documents

Catalytic hydrogenation of α,β-unsaturated carboxylic acid derivatives using copper(i)/N-heterocyclic carbene complexes

A simple and air-stable copper(i)/N-heterocyclic carbene complex enables the catalytic hydrogenation of enoates and enamides, hitherto unreactive substrates employing homogeneous copper catalysis and H2 as a terminal reducing agent. This atom economic transformation replaces commonly employed hydrosilanes and can also be carried out in an asymmetric fashion.

Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts

The invention pertains to the use of Group 8 transition metal carbene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand are used to catalyze cross-metathesis reactions to provide a variety of substituted and functionalized olefins, including phosphonate-substituted olefins, directly halogenated olefins, 1,1,2-trisubstituted olefins, and quaternary allylic olefins. The invention further provides a method for creating functional diversity using the aforementioned complexes to catalyze cross-metathesis reactions of a first olefinic reactant, which may or may not be substituted with a functional group, with each of a plurality of different olefinic reactants, which may or may not be substituted with functional groups, to give a plurality of structurally distinct olefinic products. The methodology of the invention is also useful in facilitating the stereoselective synthesis of 1,2-disubstituted olefins in the cis configuration.

PKas of the conjugate acids of N-heterocyclic carbenes in water

pKa values of 19.8-28.2 are reported for the conjugate acids of a large series of NHCs in water. The effects of ring size, N-substituent and C(4)-C(5) saturation on pKa are discussed.