25829-83-8

Upstream product

• 32624-99-0 12α-Hydroxy-5α-cholan 
• 111659-96-2 methyl 12α-acetoxy-3-oxo-4-cholen-24-oate 
• 32624-96-7 3α,12α,24-Trihydroxy-5α-cholan 
• 5618-27-9 5α-pregnan-12,20-dione 12-ethylene acetal 
• 86691-82-9 C₃₀H₄₂O₆S 
• 58652-67-8 3β-acetoxy-12,12-ethanediyldioxy-5α-pregnan-20-one 
• 86679-54-1 12,12-ethanediyldioxy-3β-hydroxy-5α-pregnan-20-one 
• 86679-57-4 5α-chol-20(22)-en-12-one ethylene acetal 
• 86679-60-9 5α-chol-20(22)-en-12-one 

Relevant academic research and scientific papers

SYNTHESIS OF A SERIES OF 12-OXO-5α-STEROIDS WITH VARIABLE 17β-SIDE CHAIN

5α-Androstan-12-one and its homologues up to 5α-cholan-12-one were synthesized, partly by breaking down the 17β-side chain of 5α-pregnan-12,20-dione 12-ethylene acetal 7 and partly by means of Wittig condensation reactions.They were all characterized by their spectral properties.

Conformational analysis-LII. The conformation of ring a in 5β-3-ketosteroids

5β-Cholane-3,12-dione has been synthesized, and its dipole moment measured in benzene solution. The value of 4·49 D shows that ring A is in the chair form to within the limits of experimental measurement, which indicates that the earlier interpretation of the dipole moment of 5β-androstan-3,17-dione in terms of an equilibrium mixture of boat and chair forms for ring A is improbable, and that the later compound is more likely to have a deformation present in ring D.