258356-22-8

Upstream product

• 17466-06-7 3-p-tolyl-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidine-7-thione 
• 74-88-4 methyl iodide 
• 17465-99-5 7-chloro-3-(4-methylphenyl)-3H-1,2,3-triazolo<4,5-d>pyrimidine 

Downstream Products

• 258356-25-1 (3-p-tolyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-hydrazine 

Relevant academic research and scientific papers

1,2,3-Triazolo[4,5-e]-1,2,4-triazolo[3,4-c]pyrimidines

Some new 1,2,3-triazolo[4,5-e]-1,2,4-triazolo[3,4-c]pyrimidines were prepared starting from the corresponding 1,2,3-triazolo[4,5-d]pyrimidines via the formation of the 1,2,4-triazole ring. Thus suitable hydrazino derivatives 6 were condensed with triethyl orthoformate, triethyl orthoacetate and triethyl orthobenzoate to give the expected tricyclic derivatives 7, 8 and 9. Intramolecular cyclization of the ethoxycarbonylhydrazino derivatives 10 gave the tricyclic compounds 11 bearing an hydroxyl group in the 3 position. The v-triazolo-s-triazolopyrimidine derivatives were tested towards the A1 and A(2A) adenosine receptors in binding assays, but they did not show any receptor affinity.