Cas 25850-25-3,2-[2-[4-(1-pyrrolidinyl)phenyl]ethenyl]-1,3,3-trimethyl-3H-indolium iodide

25850-25-3

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Basic information

Product Name: 2-[2-[4-(1-pyrrolidinyl)phenyl]ethenyl]-1,3,3-trimethyl-3H-indolium iodide
Synonyms:
CAS NO:25850-25-3
Molecular Formula:
Molecular Weight: 458.385
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2-[2-[4-(1-pyrrolidinyl)phenyl]ethenyl]-1,3,3-trimethyl-3H-indolium iodide(CAS DataBase Reference)
NIST Chemistry Reference: 2-[2-[4-(1-pyrrolidinyl)phenyl]ethenyl]-1,3,3-trimethyl-3H-indolium iodide(25850-25-3)
EPA Substance Registry System: 2-[2-[4-(1-pyrrolidinyl)phenyl]ethenyl]-1,3,3-trimethyl-3H-indolium iodide(25850-25-3)

Safety Data

Hazard Codes: N/A
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Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 25850-25-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 25850-25-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,8,5 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 25850-25:
(7*2)+(6*5)+(5*8)+(4*5)+(3*0)+(2*2)+(1*5)=113
113 % 10 = 3
So 25850-25-3 is a valid CAS Registry Number.

25850-25-3Upstream product

25850-25-3Downstream Products

25850-25-3Relevant academic research and scientific papers

OFF/ON Red-Emitting Fluorescent Probes for Casein Recognition and Quantification Based on Indolium Derivatives

Yang, Wei,Liu, Chunlin,Gao, Qingyun,Du, Jinya,Shen, Ping,Yang, Changying

, p. 391 - 398 (2017)

Five derivatives of 2, 3, 3-trimethyl-3H-indolium containing different electron donor groups (H1 - H5) were synthesized for the determination of proteins. H3, a sensitive red-emitting fluorescent probe, was found for the discrimination of hydrophobic prot

2-Styrylindolium based fluorescent probes visualize neurofibrillary tangles in Alzheimer's disease

Gu, Jiamin,Anumala, Upendra Rao,Lo Monte, Fabio,Kramer, Thomas,Heyny Von Haussen, Roland,Hoelzer, Jana,Goetschy-Meyer, Valerie,Mall, Gerhard,Hilger, Ingrid,Czech, Christian,Schmidt, Boris

, p. 7667 - 7671 (2013/02/22)

We evaluated 2-styrylindolium derivatives (6-11) as novel and selective probes for neurofibrillary tangles (NFTs) on brain sections of AD patients. The staining experiments indicated that these compounds may bind selectively to NFTs in the presence of ss-amyloid (Ass) plaques. Cell free binding assays confirmed that 2-[2-[4-(1-pyrrolidinyl)phenyl]ethenyl]-1,3,3-trimethyl-3H- indolium iodide (9) and 2-[2-[4-(diethylamino)phenyl]ethenyl]-1-butyl-3,3- dimethyl-3H-indolium iodide (11) display excellent affinities to Tau-aggregates (IC50 values of 5.1 and 1.4 nM, respectively) in the displacement of Thiazin Red R. These probes have good solubility in distilled water and low or no cytotoxicity in zebrafish embryo and liver hepatocellular carcinoma cell assays.

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