258503-06-9

Basic information

• Product Name: 2-chloro-N-[2-methyl-5-(2-morpholinopyrid-4-ylcarbonylamino)phenyl]pyridine4 carboxamide
• Synonyms: 2-chloro-N-[2-methyl-5-(2-morpholinopyrid-4-ylcarbonylamino)phenyl]pyridine4 carboxamide
• CAS NO: 258503-06-9
• Molecular Weight: 451.912
• Mol File: 258503-06-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-N-[2-methyl-5-(2-morpholinopyrid-4-ylcarbonylamino)phenyl]pyridine4 carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-[2-methyl-5-(2-morpholinopyrid-4-ylcarbonylamino)phenyl]pyridine4 carboxamide(258503-06-9)
• EPA Substance Registry System: 2-chloro-N-[2-methyl-5-(2-morpholinopyrid-4-ylcarbonylamino)phenyl]pyridine4 carboxamide(258503-06-9)

Safety Data

• Hazardous Substances Data: 258503-06-9(Hazardous Substances Data)

Upstream product

• 65287-34-5 2-chloropyridine-4-carbonyl chloride 
• 258503-86-5 N-(3-amino-4-methylphenyl)-2-morpholinopyridine-4-carboxamide 

Relevant articles and documents

Amide derivatives useful as inhibitors of the production of cytokines

The invention concerns amide derivatives of formula (I) wherein R3is (1-6C)alkyl or halogeno; Q1is heteroaryl which is optionally substituted with 1, 2, 3, or 4 substituents such as hydroxy, halogeno, trifluoromethyl, (1-6C)alkyl, (1-6C)alkoxy, hydroxy-(1-6C)alkyl, (1-6C)alkoxy-(1-6C)alkyl, hydroxy-(2-6C)alkoxy, amino-(2-6C)alkylamino, N-(1-6C)alkyl-(1-6C)alkylamino-(2-6C)alkylamino, aryl, heteroaryl and heterocyclyl; p is 0-2 and R2is a substituent such as hydroxy and halogeno; q is 0-4; and Q2includes optionally substituted aryl, cycloalkyl, heteroaryl and heterocyclyl; or pharmaceutically-acceptable salts or in vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.