25860-27-9Relevant academic research and scientific papers
Clay-catalyzed solventless addition reactions of furan with α,β- unsaturated carbonyl compounds
Avalos, Martin,Babiano, Reyes,Bravo, Jose L.,Cintas, Pedro,Jimenez, Jose L.,Palacios, Juan C.
, p. 9301 - 9304 (2007/10/03)
The reaction of furan with α,β-unsaturated carbonyl dienophiles catalyzed by K10 montmorillonite in the absence of organic solvents produces the corresponding Diels-Alder adducts and, in the case of methyl vinyl ketone, Michael-type products, under much milder conditions than the conventional protocols. The results are consistent with acid catalysis on the clay surface. Acrylates gave lower yields and/or decomposition products. The reaction can be extended to alkynic substrates such as DMAD to afford cycloadducts in good yields.
