258883-70-4Relevant academic research and scientific papers
Efficient synthesis of 2- and 3-substituted-2,3-dihydro [1,4]dioxino[2,3-b]pyridine derivatives
Lazar,Soukri,Leger,Jarry,Akssira,Chirita,Grig-Alexa,Finaru,Guillaumet
, p. 6461 - 6473 (2007/10/03)
A versatile new approach for the synthesis in three steps of 2-substituted-2,3-dihydro[1,4]dioxino[2,3-b]pyridines B via a Smiles rearrangement using easily available reagents is described. A study illustrating the influence of experimental conditions on the progress of the reaction is reported.
Synthesis of various analog derivatives of ORG13514 as 5-HT(1A) ligands
Comoy, Corinne,Benarab, Abdelhakim,Leinot, Michel,Monteil, Andre,Guillaumet, Gerald
, p. 791 - 799 (2007/10/03)
In connection with the development of new potential 5-HT(1A) ligands, multistep synthesis of N-substituted-3-aminomethyl-2,3-dihydro-1,4- dioxinol[2,3-b]pyridine derivatives as ORG13514 analogs are described. Their biological activity as 5-HT(1A) type lig
