25911-74-4 Usage
Uses
Used in Food Industry:
2-Amino-3-aminomethylpyrazine serves as a flavoring agent, imparting a roasted, nutty, and meaty taste to a variety of food products. It is commonly used in coffee, chocolate, and grilled meats, enhancing their flavor profiles and consumer appeal.
Used in Pharmaceutical Production:
2-AMINO-3-AMINOMETHYLPYRAZINE also finds its application in the production of pharmaceuticals, where it plays a crucial role in the development of various medicinal formulations.
Used in Organic Synthesis:
2-Amino-3-aminomethylpyrazine acts as a building block in organic synthesis, contributing to the creation of complex organic compounds for diverse applications.
However, it is important to handle 2-Amino-3-aminomethylpyrazine with care due to its potential hazards in industrial and laboratory settings. Proper safety measures should be implemented to ensure its safe use.
Check Digit Verification of cas no
The CAS Registry Mumber 25911-74-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,9,1 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25911-74:
(7*2)+(6*5)+(5*9)+(4*1)+(3*1)+(2*7)+(1*4)=114
114 % 10 = 4
So 25911-74-4 is a valid CAS Registry Number.
25911-74-4Relevant academic research and scientific papers
Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)
Lin, Songnian,Lombardo, Matthew,Malkani, Sunita,Hale, Jeffrey J.,Mills, Sander G.,Chapman, Kevin,Thompson, James E.,Zhang, Wen Xiao,Wang, Ruixiu,Cubbon, Rose M.,O'Neill, Edward A.,Luell, Silvi,Carballo-Jane, Ester,Yang, Lihu
scheme or table, p. 3238 - 3242 (2010/05/02)
Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas are described as inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). These compounds demonstrate potent in vitro activity against the enzyme with IC50 values as low as 15 nM, and suppress expression of TNFα in THP-1 cells and in vivo in an acute inflammation model in mice. The synthesis, structure-activity relationship (SAR), and biological evaluation of these compounds are discussed.
