259148-89-5

Basic information

• Product Name: Thiophene, 2-bromo-3-(4-methylphenyl)-
• CAS NO: 259148-89-5
• Molecular Formula: C11H9BrS
• Molecular Weight: 253.162
• Mol File: 259148-89-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Thiophene, 2-bromo-3-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 2-bromo-3-(4-methylphenyl)-(259148-89-5)
• EPA Substance Registry System: Thiophene, 2-bromo-3-(4-methylphenyl)-(259148-89-5)

Safety Data

• Hazardous Substances Data: 259148-89-5(Hazardous Substances Data)

Upstream product

• 51431-59-5 2-(p-tolyl)but-3-en-2-ol 
• 16939-05-2 3-(4-tolyl)thiophene 

Downstream Products

• 259148-91-9 2-[chloro(diisopropyl)silyl]-3-(p-tolyl)thiophene 
• 259148-93-1 2-(3-p-tolyl-2-thienyl)-1,3,2-dioxaborinane 

Relevant articles and documents

Redox-Divergent Construction of (Dihydro)thiophenes with DMSO

Thiophene-based rings are one of the most widely used building blocks for the synthesis of sulfur-containing molecules. Inspired by the redox diversity of these features in nature, we demonstrate herein a redox-divergent construction of dihydrothiophenes, thiophenes, and bromothiophenes from the respective readily available allylic alcohols, dimethyl sulfoxide (DMSO), and HBr. The redox-divergent selectivity could be manipulated mainly by controlling the dosage of DMSO and HBr. Mechanistic studies suggest that DMSO simultaneously acts as an oxidant and a sulfur donor. The synthetic potentials of the products as platform molecules were also demonstrated by various derivatizations, including the preparation of bioactive and functional molecules.