259152-13-1Relevant academic research and scientific papers
Ring-fluorinated isoquinoline and quinoline synthesis: Intramolecular cyclization of o-cyano- and o-isocyano-β,β-difluorostyrenes
Ichikawa, Junji,Wada, Yukinori,Miyazaki, Hiroyuki,Mori, Takashi,Kuroki, Hiroyuki
, p. 1455 - 1458 (2007/10/03)
(Matrix presented) o-Cyano-β,β-difluorostyrenes react with organolithiums selectively at the cyano carbon to generate the corresponding sp2 nitrogen anions, which in turn undergo intramolecular replacement of the vinylic fluorine to afford 3-fl
