259248-36-7Relevant academic research and scientific papers
Preparation of O-Protected Cyanohydrins by Aerobic Oxidation of α-Substituted Malononitriles in the Presence of Diarylphosphine Oxides
Zhang, Dapeng,Lian, Mingming,Liu, Jia,Tang, Shukun,Liu, Guangzhi,Ma, Cunfei,Meng, Qingwei,Peng, Haisheng,Zhu, Daling
supporting information, p. 2597 - 2601 (2019/04/17)
A mild, reagent-cyanide-free, and efficient synthesis of O-phosphinoyl-protected cyanohydrins from readily available α-substituted malononitriles was realized using diarylphosphine oxides in the presence of O2. Mechanistic studies indicated that in addition to the initial aerobic oxidation of the malononitrile derivative notable features of this process include the formation of a tetrahedral intermediate and a subsequent intramolecular rearrangement. The phosphinoyl-protecting group can be removed by alcoholysis or by reduction with DIBAL-H.
MESOIONIC PESTICIDES
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Page/Page column 119, (2011/02/24)
Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein (Formula 1) X is O or S; Y is O or S; A is O, S, NR3e or C(R3c)=C(R3d); Z is a direct bond, O, S(O)n,191, NR6, C(R7/sup
