259262-24-3 Usage
General Description
4-[2-Chloro-5-[3(R)-pyrrolidinyloxy]pyridin-3-yl]benzonitrile is a chemical compound with the molecular formula C19H15ClN4O. It is a derivative of pyridine and benzonitrile, containing a chlorine atom and a pyrrolidinyl group. 4-[2-Chloro-5-[3(R)-pyrrolidinyloxy]pyridin-3-yl]benzonitrile has potential applications in the field of medicinal chemistry, as it may exhibit pharmacological properties due to its unique structure. It could be used as a building block for the synthesis of novel pharmaceutical compounds. Additionally, it may also have applications in the area of agrochemicals and material science. Further research and studies are needed to fully understand the potential uses and properties of this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 259262-24-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,9,2,6 and 2 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 259262-24:
(8*2)+(7*5)+(6*9)+(5*2)+(4*6)+(3*2)+(2*2)+(1*4)=153
153 % 10 = 3
So 259262-24-3 is a valid CAS Registry Number.
259262-24-3Relevant articles and documents
PYRIDYL ETHERS AND THIOETHERS AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTOR AND ITS THERAPEUTIC APPLICATION
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Page 14, (2010/02/07)
The present invention provides compounds of the formula:wherein m is 0, 1 or 2; p is 0 or 1; Y is O, S, S(O) or S(O)2 and R1 to R7 are various substituents as selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Al
Synthesis and structure-activity relationship of novel pyridyl ethers for the nicotinic acetylcholine receptor
Lee, Jung,Davis, Coralie B.,Rivero, Ralph A.,Reitz, Allen B.,Shank, Richard P.
, p. 1063 - 1066 (2007/10/03)
The preparation of novel pyridyl ethers as ligands for the nicotinic acetylcholine receptor (nAChR) is described. Variations of the ring size of the azacycle and substitution on the pyridine had dramatic effects on receptor binding affinity with IC50S at the α4β2 nAChR ranging from 22 to >10,000 nM. The most potent molecule was (R)-2-chloro-3-(4-cyanophenyl)-5-((3-pyrrolidinyl)oxy)pyridine 27f with an IC50 of 22 nM. (C) 2000 Elsevier Science Ltd. All rights reserved.
