25939-33-7Relevant articles and documents
Preparation of methyl N-substituted carbamates from amides through N-chloroamides
Hiegel, Gene A.,Hogenauer, Tyrone J.
, p. 2091 - 2098 (2005)
Amides are chlorinated on the nitrogen using trichloroisocyanuric acid, and the N-chloroamides are then rearranged to the corresponding methyl N-substituted carbamates by sodium methoxide in methanol. Copyright Taylor & Francis, Inc.
A simple protocol for efficient N-chlorination of amides and carbamates
De Luca, Lidia,Giacomelli, Giampaolo,Nieddu, Giammario
, p. 223 - 226 (2007/10/03)
N-Chlorination of various amides, lactams, and carbamates with very cheap trichloroisocyanuric acid proceeds efficiently under very mild conditions. Excellent results were also observed for the N-chlorination of carbamates of free amino acids.
